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Animal Follicular Fluid Metabolomics

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Animal Follicular Fluid Metabolomics Services Flow Chart Applications Why Choose Us

Animal Follicular Fluid Metabolomics Services

Follicular fluid protects the oocyte from protein degradation and expulsion during ovulation, while also creating an optimal microenvironment for the proper development of the embryo. Follicular fluid plays a crucial role in embryo quality and is a research subject directly related to animal breeding. BioVenic conducts untargeted metabolomic analysis of animal follicular fluid samples to provide metabolic information for global scientific researchers studying intrafollicular signaling pathways, follicle growth and development, egg quality, fertility, reproductive health, and diseases. Our comprehensive service offers a metabolomic analysis of follicular fluid. It serves as a high-throughput scientific research tool for evaluating companion animal and livestock fertility and reproductive capabilities.

Fig.1 Schematic Diagram of Goat Follicular Fluid Metabolomics Analysis. (Arcce, et al., 2023) Fig.1 Schematic Diagram of Goat Follicular Fluid Metabolomics Analysis. 1

Animal Follicular Fluid Metabolomics Services

We offer personalized metabolomics solutions for scientists conducting research on female reproductive health and disease. BioVenic's one-stop solution ranges from follicular fluid sampling, pretreatment, metabolite detection and identification, to analysis of non-targeted physiological and metabolic activities. Utilizing a combination of multiple biochemical detection technologies, we thoroughly identify specific components in follicular fluid. This approach allows our customers to gain a better understanding of intracellular signal transduction and uncover potential biomarkers of oocyte health. Ultimately, this research provides new directions for the treatment of reproductive diseases.

Flow Chart of Animal Non-targeted Metabolomics Analysis Service

Fig.2 Flow Chart of Animal Non-targeted Metabolomics Analysis Service. (BioVenic Original)

Applications of Animal Follicular Fluid Metabolomics Services

  • Embryo Quality-related Biomarkers Discovery

As a physiological component in direct contact with the animal embryo, the composition, and changes of metabolites in the follicular fluid directly reveal the life activities between the embryo and the mother. Metabolomic analysis of animal follicular fluid can monitor the entire process of embryonic growth and development. Evaluate the quality and health of animal embryos through dynamic analysis of levels of specific biomarkers with high correlation. It is a crucial prerequisite to find new biomarkers that are highly correlated with egg quality through metabolomic data analysis.

  • Oocyte Quality Evaluation

As an intuitive and rigorous scientific detection tool, metabolomics can visualize the developmental status and health of oocytes through the levels and dynamic changes of certain metabolites. Compared with other detection methods, follicular fluid metabolomics more truly reflects the growth and development of follicles.

  • Female Reproductive Improvement

Metabolomics analysis of follicular fluid has been utilized in numerous scientific research projects focused on female reproductive capability enhancement. The use of non-targeted metabolomics to identify ovarian activity reflects an individual's reproductive ability to a certain extent. At the same time, analyzing the differences in related biomarkers in reproduction offers a new avenue for the development of novel treatments for improving animal reproduction.

Why Choose Us?

Multiple metabolic component detection methods ensure thorough analysis of samples.

The high resolution and stability fully guarantee the accuracy and repeatability of experimental results.

The expert technical support service team has rich experience in animal metabolome experiments.

Design customized metabolomics solutions based on client specific project needs.

BioVenic uses a high-throughput comprehensive bioassay platform and a self-developed metabolomics data processing system to provide customers with one-stop non-targeted metabolomics services for animal follicular fluid. Just communicate with us about your specific scientific research needs, and the exclusive metabolomics solution designed by the expert team will be accurately carried out from sample preparation, data information processing and effective extraction, metabolic pathway analysis and statistical reporting through multiple optimized standardized experimental procedures. Based on BioVenic's self-built database containing a variety of small molecule metabolites, this service can accurately and efficiently analyze follicular fluid samples, with high coverage of almost all small molecules in them. This ensures that the test data reflects the growth, development, and quality of follicles to the greatest extent. It also provides new exploratory perspectives for improving reproductive capability among animals. If you are conducting scientific research in the aforementioned areas or require assistance with implementing high-throughput metabolomics technology, please do not hesitate to contact us.

Reference

  1. Arcce, Irving Mitchell Laines, et al. "Nuclear magnetic resonance-based metabolomics in goat ovarian follicular fluid." Small Ruminant Research 223 (2023): 106968.
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