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Veterinary Fungal Pathogen Transcriptomics Services
Biovenic's veterinary fungal pathogen transcriptomics services are specifically tailored for research and development in veterinary medicine. Our services are designed to provide researchers with comprehensive insights into the gene expression profiles of fungal pathogens affecting animals. By leveraging cutting-edge transcriptomics technologies, we aim to advance the understanding of animal fungal diseases, enhance the development of novel vaccines and therapeutics, and contribute to the overall health and well-being of animals.
Veterinary Fungal Pathogen Transcriptomics Services
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Sample Preparation
We start with meticulous sample preparation to ensure the integrity and quality of RNA, which is crucial for accurate transcriptomic analysis. We use advanced extraction techniques to obtain high-quality RNA from a variety of veterinary samples, including tissues, body fluids, and cultured fungal cells. We employ bioanalyzers and spectrophotometers to assess RNA integrity, concentration, and purity, ensuring that only high-quality RNA is used for sequencing. -
Sequencing Technologies
We offer a range of sequencing technologies tailored to the specific needs of your research. We offer comprehensive microarray and RNA-Seq services to help you obtain valuable insights from your sequencing data. Our service is designed to handle the entire process, ensuring high-quality results tailored to your specific experimental needs.Method RNA-Seq Microarray Throughput High Higher Input RNA Amount ~ 1 ng total RNA ~ 1 μg mRNA Intensity High Low Quantitation Accuracy ~ 90% > 90% Sequence Resolution SNPs and splice variants Splice variants Sensitivity 10-6 10-3 Dynamic Range > 10-5 10-3-10-4 Technical Reproducibility > 99% > 99% -
Bioinformatic Analysis
Our bioinformatics team provides comprehensive data analysis to transform raw sequencing data into meaningful biological insights.- Read Mapping and Alignment: Aligning sequencing reads to reference genomes or transcriptomes to identify expressed genes.
- Differential Expression Analysis: Comparing gene expression levels between different conditions or treatments to identify differentially expressed genes.
- Pathway and Functional Analysis: Annotating genes and mapping them to biological pathways to understand their roles in fungal pathogenicity and drug resistance.
- Gene Co-expression Networks: Constructing networks to identify gene modules and key regulatory genes involved in fungal responses.
Fig.1 Flowchart for the dual RNA-seq protocol.1
Services Workflow
Applications
Fungal infections in animals can lead to severe health issues, impacting livestock productivity and pet health. Understanding the gene expression profiles of these pathogens can help in fungal disease research and development.
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Developing molecular markers for early and accurate detection of fungal infections. Our services support the development of diagnostic tools for early and accurate detection of fungal infections. Discovering molecular markers specific to different fungal species and strains. Developing rapid diagnostic tests based on the expression profiles of these markers. Enhancing the sensitivity and specificity of existing diagnostic assays. |
Fungal pathogens have developed various mechanisms to evade the effects of antifungal drugs, posing significant challenges in veterinary medicine. Our transcriptomics services play a crucial role in understanding and combating drug resistance in fungal pathogens. By analyzing the transcriptome of fungal pathogens exposed to antifungal agents, we can identify genes and pathways involved in drug resistance. |
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By studying the immune response of animals to fungal infections, researchers can identify antigens that elicit strong immune responses, which can be used as vaccine candidates. Understand the molecular mechanisms of immune evasion by fungal pathogens, helping to design more effective vaccines. Monitor the efficacy of vaccine candidates by comparing the transcriptomes of vaccinated and unvaccinated animals. |
Understanding the pathogenesis of fungal infections is essential for developing effective preventive and therapeutic strategies. Our transcriptomics services provide valuable insights into the molecular mechanisms underlying fungal infections in animals. Transcriptomics can elucidate the complex interactions between fungal pathogens and their animal hosts by host transcriptome in response to fungal infections and gene expression of fungal evasion to the host's immune response, as well as identifying and characterizing virulence factors that contribute to the pathogenicity of fungal infections. |
Why Choose Us?
- Our team comprises experienced molecular biologists, bioinformaticians, and veterinarians with extensive knowledge in fungal pathogen research and transcriptomics.
- Our flexible service offerings allow us to tailor our approach to meet your specific needs, ensuring that you receive the most relevant and actionable data for your research objectives.
- We adhere to stringent quality control measures to ensure the reliability and reproducibility of our results.
BioVenic's veterinary fungal pathogen transcriptomics services offer a powerful tool for advancing research and development in veterinary medicine. By providing detailed insights into the gene expression profiles of fungal pathogens, we help researchers understand the mechanisms of pathogenesis, drug resistance, and host interactions. Our comprehensive and customizable services can support your research needs in developing new antifungal drugs, vaccines, or diagnostic tools. Please contact us to learn more about our fungal pathogen transcriptomics services.
Reference
- Enguita, Francisco J., et al. "Transcriptomic crosstalk between fungal invasive pathogens and their host cells: opportunities and challenges for next-generation sequencing methods." Journal of Fungi 2.1 (2016): 7.