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Hybrid Phage Veterinary Vaccine Development
Both phage display veterinary vaccines and phage DNA veterinary vaccines offer distinct advantages. Hybrid phage veterinary vaccines, on the other hand, represent a fusion of these two vaccine technologies. They not only leverage the phage display of antigenic proteins or peptides but also incorporate eukaryotic expression cassettes that encode the target antigens directly into their genome. This innovative approach leads to a more robust protective immune response. BioVenic boasts extensive experience in supporting researchers in their endeavors to develop phage-based veterinary vaccine projects. We provide comprehensive and efficient one-stop services for the development of hybrid phage veterinary vaccines. Our aim is to assist you in harnessing this emerging technology to combat infections caused by viral or bacterial pathogens.
Our Services
The development of hybrid phage veterinary vaccines is based on the combination of phage display veterinary vaccines and phage DNA veterinary vaccines. BioVenic has rich project service experience in the development of these two types of phage veterinary vaccines mentioned above, and therefore also has the ability to provide you with hybrid phage veterinary vaccine development services, the details of the services can be found in the following links.
Fig.1 Schematic structures of three types of phage-based vaccines 1
Hybrid Phage Veterinary Vaccine Development Services
Phages are gaining popularity in the field of veterinary vaccine development due to their excellent safety profile. The adjuvant properties enhance the immune response of hybrid phage vaccines, which addresses issues related to the low immunogenicity and adjuvant requirements of DNA veterinary vaccines. BioVenic specializes in helping design vaccine formulations that are tailored to the characteristics of veterinary vaccines, reducing the discomfort associated with injection and improving the vaccine's absorption efficiency in host animals.
BioVenic offers a wide range of assessments with a strong focus on vaccine safety, efficacy, and immunogenicity, which ensure high-quality immune protection without causing adverse reactions in livestock, poultry, companion animals, aquaculture species and more. We maintain stringent quality control throughout the entire veterinary vaccine development process. This includes rigorous control of raw materials and production conditions, ensuring the stability and batch consistency of your veterinary vaccines.
Why Choose Us?
Extensive experience in phage-based veterinary vaccine development.
Comprehensive service offerings for both types of phage-based veterinary vaccines, whether single or hybrid.
In the case of hybrid phage veterinary vaccines, peptides and DNA are delivered using one single phage. By inserting the DNA encoding protective antigens into the phage genome while displaying antigenic peptides on the phage surface, they exhibit a superior ability to stimulate host animals to generate protective immune responses compared to phage display vaccines or phage DNA vaccines only. BioVenic is committed to applying new technologies, thus accumulating rich experience in phage-based veterinary vaccine development. We will do our utmost to guide on a successful path in hybrid phage veterinary vaccine development for animals. Please contact us, and let's combat animal pathogen infections and safeguard animal health!
Reference
- González-Mora, Alejandro, et al. "Bacteriophage-based vaccines: A potent approach for antigen delivery." Vaccines 8.3 (2020): 504.