This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Live Attenuated Veterinary Vaccine Development
Live attenuated vaccine is the first type of vaccine to be used, and the vast majority of vaccines currently used in animals are of this type. BioVenic offers development services for live attenuated veterinary vaccines with extensive experience as a traditional vaccine type, giving you a safe and efficient option. Explore our comprehensive services that combine scientific innovation with practical applications to enhance animal health and well-being.
Fig.1 How to be live attenuated vaccines? (BioVenic Original)
Types of Pathogens Suitable for Live Attenuated Vaccines
Live attenuated veterinary vaccines are suitable for various types of pathogens, besides viruses there are also bacteria, parasites, etc. Company provides a platform for the development of them to help researchers protect against many types of pathogens.
| Pathogen Types | Examples |
|---|---|
| Virus | Canine morbillivirus, Bluetongue virus, Rabies lyssavirus, canine adenovirus, avian infectious bronchitis virus. |
| Bacteria | Brucella melitensis, Salmonella gallinarum, Escherichia coli, Chlamydophila abortus. |
| Parasite | Cattle lungworm Dictyocaulus viviparus. |
| Protozoa and Rickettsia | Ehrlichia ruminantium, Theileria annulate. |
| Fungi | Trichophyton verrucosum. |
Our Services
Attenuation
The attenuation of pathogens is a critical step in live attenuated veterinary vaccine development. BioVenic offer attenuation services for vaccine development, guaranteeing proper immunogenicity of veterinary vaccines.
Safety Assessment
BioVenic's comprehensive safety assessment process includes rigorous testing and analysis to evaluate the potential risks of live attenuated veterinary vaccines through a series of in vivo and in vitro experiments, including animal behavioral observations, histopathology, blood biochemistry, and other tests. We also conduct overdose tests on live vaccines for the sake of live vaccines. These assessments are conducted to determine attenuated veterinary vaccine's safety and to identify and resolve any potential problems.
Reversion to Virulence Assessment
Live attenuated veterinary vaccines have the potential risk of regaining their original virulence, which poses a safety concern. To address this risk, BioVenic offers a specialized service called "reversion to virulence assessment", which uses the vaccine to conduct health assessments on consecutive generations of susceptible animals, and then samples and verifies them using molecular and serological experiments to analyze whether there is any reversion of virulence. Our target is to reduce the risk of vaccine-related adverse events.
Immunogenicity Assessment
The primary goal in the live attenuated veterinary vaccine development is to elicit a strong protective immune response in the animal. BioVenic offers immunogenicity assessment services. Our team of experienced scientists uses advanced technology to measure the vaccine immunogenicity. This assessment includes analyzing the levels of antibodies, cytokines and other immune markers induced by live attenuated veterinary vaccines. By measuring the immune response, we gauge the vaccine's ability to effectively stimulate the immune system, giving our clients a comprehensive understanding of their live attenuated veterinary vaccines' performance, which can then be used to optimize vaccine formulation and design.
Formulation Development and Quality Control
Formulation development and quality control are critical stages in the development of live attenuated veterinary vaccines to ensure the safety, efficacy and stability of the final product. Formulation development includes optimization of the vaccine composition, and although live attenuated veterinary vaccines do not require adjuvant addition, stabilizers and preservatives are still needed to improve the stability of the vaccine. Quality control involves a rigorous series of tests and analyses to assess vaccine identity, purity, efficacy and safety.
BioVenic is your ideal partner in live attenuated veterinary vaccine development. Backed by our extensive expertise, BioVenic offers a collaborative approach to ensure that veterinary vaccine candidates meet the highest standards of safety, immunogenicity and efficacy, protecting livestock, poultry, companion animals, aquaculture species and more. Contact us now! Choose us as your trusted ally to help you navigate the complexities of live attenuated vaccine development and bring innovative solutions to the forefront of veterinary health.