Monogastric Animal Fermentation Solution

The microbial composition within monogastric animal (including pigs, poultry, felines, canines, horses) gastrointestinal tract (GIT) can vary among different animal species, breeds, and sections of their GIT. Additionally, they exhibit distinct fermentation characteristics for the nutrients in their feed. To aid researchers in monogastric nutrition, BioVenic offers monogastric animal fermentation solution that encompasses both in vitro and in vivo fermentation studies, feed analysis, microbiological analysis, and metabolite analysis. This comprehensive solution facilitates the study of microbial fermentation characteristics of monogastrics, thus assisting in monogastric nutrition development.

Monogastric Animal Fermentation One-Stop Solution

Our monogastric animal fermentation research encompasses both in vitro and in vivo studies. Our in vitro platform offers a cost-effective alternative for studying fermentation processes. For in vivo experiments, we utilize a variety of experimental animals, including pigs, poultry, and companion animals. Moreover, we provide customized model development solutions tailored to meet your specific research requirements.

Monogastric Animal Fermentation In Vitro Study

With extensive experience in exploring monogastric animal fermentation physiology, BioVenic offers tailored in vitro fermentation study solutions to animal nutrition researchers. Our specialized in vitro fermentation model development for monogastric animals concentrates on simulating microbial fermentation processes within the large intestine and cecum, providing valuable insights for research purposes.

Monogastric Animal Fermentation In Vivo Study

Monogastric intestine, particularly the hindgut, contains a significant population of bacteria-dominated microorganisms. The composition of these microorganisms varies in different animal types and different section of monogastric digestive system. By studying the in vivo fermentation of a variety of monogastric animals, we help explore the effects of factors such as diet, environment, breed, age, etc. on the composition of fermentation microorganisms and fermentation products in monogastric animals.

Fig. 1 The core and abundant bacteria genera in different sections of pig GIT¹

With our in vivo research platform for monogastric animals, we support fermentation studies in a variety of monogastric animals such as canines, felines, pigs, horses, poultry, etc. Our research platform covers a wide range of sample types: including animal digestive chyme (duodenum, jejunum, ileum, colon, cecum, rectum), feces, fermented feed, etc. Our main research methods include: qPCR, 16S rRNA sequencing, metagenomic sequencing, chemical composition and digestibility analysis, animal metabolite analysis, etc. It can help researchers to perform in vivo fermentation studies in animals in the following areas:

• Effect of dietary intervention on microbes in the digestive tract of monogastric animals
• Effect of drugs or feed additives on microorganisms in the digestive tract of monogastric animals
• Differences in gut microbiota at different digestive sites
• Changes in gut microbiota in monogastric animals at different growth stages
• And more.

Monogastric Animal Fermentation Microbiological Analysis

• Microbiota Analysis for Monogastric Animal Fermentation Study

Monogastric animals of various species and breeds exhibit differences in microbial composition across different intestinal segments. These variations affect the efficiency of feed nutrient utilization and subsequently impact the host animal. Additionally, microbial compositions vary depending on in vitro fermentation substrates and conditions. Our advanced platform offers comprehensive microbiome analysis solutions for fermentation studies in monogastric animals, utilizing techniques such as 16S, 18S rRNA, and ITS sequencing along with related data analysis services. These tools aid in exploring the structure and function of microbiota during the fermentation process. Our Microbial Metabolites Analysis further provides essential insights into microbiota-related metabolisms in these studies.

Our one-stop solutions for monogastric animal fermentation microbiota analysis include:

• Development of sampling and sample storage methods

According to your sample type and sampling site, we recommend existing products or custom sampling and storage methods for you.

• Sequencing services

Based on the type of microbiome to be detected, we select the appropriate sequencing region, design suitable primers, and conduct sequencing.

• Microbiota data analysis

Depending on your monogastric animal in vitro and in vivo fermentation research needs, we offer a variety of bioinformatics analysis services, including microbial diversity analysis, biomarker analysis, function analysis, and more.

• Microbial Identification for Fermentation Models in Monogastric Animals

To study the presence, absence, and quantity of specific microorganisms during fermentation, isolation and culture, or molecular biology methods for detection are often necessary. We offer a wide range of products and technology platforms for isolating, characterizing, and detecting microorganisms associated with in vivo and in vitro fermentation models. Our services include:

Monogastric Fermentation Study Metabolite Analysis

The microflora in the GIT tract plays a crucial role in nutrient digestion, absorption, and synthesis. Microbes produce proteins, amino acids, enzymes, fatty acids, and various vitamins for the host's nutrition. Our metabolite assay services enable the measurement of single metabolites in fermentation models of monogastric animals or conduct targeted/ non-targeted metabolomics. These solutions aid animal nutrition researchers in exploring the intricate mechanisms between microorganisms and the digestive tract of monogastric animals.

Please check the following links for more information on our services.

Animal Feed Analysis for Monogastric Animal Fermentation Study

Our animal feed analysis service enables researchers to evaluate routine nutritional compositions as well as customized indicators (such as mycotoxins and antinutritional factors) in feeds, monogastric animal digesta, in vitro fermentation products, and fecal samples. This analysis helps animal nutrition researchers comprehend the changes in nutrients or harmful components of a feed before and after fermentation in monogastric models, facilitating the development of new feeds.

Applications of Monogastric Animal Fermentation

• Probiotics Discovery

By cultivating microbial communities and identifying beneficial microorganism, researchers may discover probiotics for the nutrition and health of monogastric animals.

• Feed Development

By studying the fermentation characteristics of specific feed in monogastric animal in vivo and in vitro fermentation models, researchers are able to develop new feed resources or additives that promote gut microbiota health.

• Mechanism Research

By utilizing in vivo and in vitro fermentation models to investigate the complex composition and functions of microorganisms in the GIT of monogastric animals, researchers can acquire valuable mechanistic support for monogastric animal nutritional studies.

Why Choose Us?

Utilizing advanced research and analysis techniques, both internal and external research platforms, BioVenic offers monogastric fermentation study service, including microbial detection and analysis, metabolite analysis, feed analysis, and other customized services for monogastric nutrition researchers. If you need a monogastric fermentation solution, please do not hesitate to contact us.

Reference

1. Liao, Shengfa F., et al. "Swine Gastrointestinal Microbiota and the Effects of Dietary Amino Acids on Its Composition and Metabolism." International Journal of Molecular Sciences 25.2 (2024): 1237.
   Under Open Access license CC BY 4.0, without modification.