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Mouse Anti-Bovine CD14 Monoclonal Antibody-[FITC]
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine CD14. It can be applied to FCM assay of bovine CD14.
Specifications
Target Information
Bovine CD14 is a critical component of the innate immune system, playing a significant role in the host defense against bacterial infections. It exists in two forms: a membrane-bound form (mCD14) and a soluble form (sCD14). The membrane-bound form is abundant on monocytes and to a lesser extent on neutrophils, while the soluble form can sensitize cells lacking mCD14, such as epithelial and endothelial cells, to lipopolysaccharide (LPS). Bovine CD14 is essential for initiating immune responses to Gram-negative bacterial infections by facilitating the recognition of LPS, a component of the bacterial cell wall.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Ibeagha-Awemu, Eveline M., et al. "Bovine CD14 gene characterization and relationship between polymorphisms and surface expression on monocytes and polymorphonuclear neutrophils." BMC genetics 9 (2008): 1-11.