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Mouse Anti-Classical Swine Fever Virus (CSFV) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for classical swine fever virus. It is affinity purified by ion-exchange. It can be applied to ELISA assays of classical swine fever Virus.
Specifications
Target Information
Classical swine fever virus (CSFV), also known as Hog Cholera Virus, is a highly contagious and often fatal disease affecting pigs. It is caused by the CSFV, a member of the Pestivirus genus within the Flaviviridae family. The virus primarily targets the epithelial cells of the pig's respiratory and digestive tracts, leading to severe clinical signs such as fever, lethargy, vomiting, diarrhea, and in severe cases, rapid death. CSFV has a single-stranded, positivesense RNA genome that encodes for structural and non-structural proteins. The Erns protein, an important non-structural protein, is involved in immune evasion by inhibiting interferon responses. The structural proteins, such as E1 and E2, are crucial for virus attachment and entry into host cells, making them key targets for vaccine development and diagnostic tests.
Shipping and Storage
This product is shipped at ambient temperature. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lamothe-Reyes, Yaneysis,, et al.. "Host cell factors involved in classical swine fever virus entry." Veterinary Research 54.1 (2023): 115.