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Mouse Anti-Porcine Aquaporin 4 Monoclonal Antibody

Cat. No.VD8N480

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for aquaporin 4. It is affinity purified by protein A. It can be applied to WB and Indirect ELISA assays of aquaporin 4.

Specifications

Application WB; Indirect ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G10N28
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Aquaporin 4
Isotype IgG2
Immunogen Recombinant protein of aquaporin 4
Purification Protein A Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine aquaporin 4 is a member of the aquaporin family of water channel proteins, which are crucial for the regulation of water homeostasis in cells and tissues. Aquaporin 4 is predominantly expressed in the brain, particularly in astrocytes, where it plays a critical role in the maintenance of brain water balance and the integrity of the blood-brain barrier. As a molecular target, aquaporin 4 is significant due to its involvement in various neurological conditions, including cerebral edema, ischemic stroke, and neuromyelitis optica. Its role in water transport across the cell membrane makes it a potential therapeutic target for modulating brain water content and improving outcomes in these conditions.

Target Aquaporin 4
Target Synonym AQP 4; AQP4
Gene ID 100126277
UniProt ID F1ST09

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Mader, Simone, et al. "Aquaporin-4 water channel in the brain and its implication for health and disease." Cells 8.2 (2019): 90.
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