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Mouse Anti-Porcine Aquaporin 4 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for aquaporin 4. It is affinity purified by protein A. It can be applied to WB and Indirect ELISA assays of aquaporin 4.
Specifications
Target Information
Porcine aquaporin 4 is a member of the aquaporin family of water channel proteins, which are crucial for the regulation of water homeostasis in cells and tissues. Aquaporin 4 is predominantly expressed in the brain, particularly in astrocytes, where it plays a critical role in the maintenance of brain water balance and the integrity of the blood-brain barrier. As a molecular target, aquaporin 4 is significant due to its involvement in various neurological conditions, including cerebral edema, ischemic stroke, and neuromyelitis optica. Its role in water transport across the cell membrane makes it a potential therapeutic target for modulating brain water content and improving outcomes in these conditions.
Shipping and Storage
This product is shipped with ice gel packs. Store at -80°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Mader, Simone, et al. "Aquaporin-4 water channel in the brain and its implication for health and disease." Cells 8.2 (2019): 90.