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Mouse Anti-Porcine Calbindin 2 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for calbindin 2. It is affinity purified by protein G. It can be applied to WB, IHC, IF/ICC, IF-P and ELISA assays of calbindin 2.
Specifications
Target Information
Porcine calbindin 2, also known as calbindin-D28k, is a vitamin D-dependent calcium-binding protein expressed in the intestines and other tissues of pigs. It plays a significant role in calcium homeostasis by facilitating the transport and solubilization of calcium within the gastrointestinal tract, thereby aiding in the absorption of this essential mineral. Calbindin 2 is a member of the EF-hand protein family, characterized by its ability to bind calcium ions, which modulates its structure and function. The protein is particularly important for maintaining the health of the intestinal epithelium and is implicated in the regulation of intracellular calcium levels, which is crucial for various cellular processes, including signal transduction and enzyme activity.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Stevenson, Leanne, et al. "Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway." Plos one 6.5 (2011): e20276.