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Mouse Anti-Porcine Calbindin 2 Monoclonal Antibody

Cat. No.VD8N237

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for calbindin 2. It is affinity purified by protein G. It can be applied to WB, IHC, IF/ICC, IF-P and ELISA assays of calbindin 2.

Specifications

Application WB; IHC; IF/ICC; IF-P; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G5N50
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Calbindin 2
Isotype IgG1
Immunogen Recombinant protein of calbindin 2
Purification Protein G Purified
Concentration 1500 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine calbindin 2, also known as calbindin-D28k, is a vitamin D-dependent calcium-binding protein expressed in the intestines and other tissues of pigs. It plays a significant role in calcium homeostasis by facilitating the transport and solubilization of calcium within the gastrointestinal tract, thereby aiding in the absorption of this essential mineral. Calbindin 2 is a member of the EF-hand protein family, characterized by its ability to bind calcium ions, which modulates its structure and function. The protein is particularly important for maintaining the health of the intestinal epithelium and is implicated in the regulation of intracellular calcium levels, which is crucial for various cellular processes, including signal transduction and enzyme activity.

Target Calbindin 2
Target Synonym CALB2
Gene ID 100127479
UniProt ID A0A8D0J7P4

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Stevenson, Leanne, et al. "Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway." Plos one 6.5 (2011): e20276.
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