Mouse Anti-Porcine Nuclear Factor Interleukin-3-Regulated Protein (NFIL3) Monoclonal Antibody

Porcine nuclear factor interleukin-3-regulated protein, also known as NFIL3 or Bcl3, is a transcription factor that plays a crucial role in immune responses and inflammation. It is regulated by various cytokines, including interleukin-3 (IL-3), and is involved in the modulation of gene expression related to immune cell function. NFIL3 is essential for the development and activation of immune cells, particularly in the context of T helper 2 (Th2) cell differentiation and the regulation of allergic reactions. The protein has been implicated in the regulation of inflammatory pathways and the control of immune cell proliferation. It interacts with other transcription factors and co-activators to modulate the expression of target genes involved in immune responses. The activity of NFIL3 can be influenced by post-translational modifications, such as phosphorylation, which can affect its stability, DNA-binding capacity, and interaction with other proteins.