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Mouse Anti-Porcine Thromboxane A Synthase 1 (TBXAS1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for thromboxane a synthase 1. It is affinity purified by protein A. It can be applied to WB, IHC, FC and ELISA assays of thromboxane a synthase 1.
Specifications
Target Information
Porcine thromboxane A synthase 1 (pTXAS1), also known as thromboxane synthase 1, is a key enzyme in the biosynthesis of thromboxane A2 (TXA2), a potent vasoconstrictor and platelet aggregator. pTXAS1 catalyzes the conversion of prostaglandin H2 (PGH2) to TXA2, playing a crucial role in the regulation of blood clotting and vascular tone. This enzyme is predominantly expressed in platelets and vascular endothelial cells, where it contributes to the maintenance of hemostasis and the response to injury. In pigs, pTXAS1 may be particularly important for the regulation of blood pressure and the prevention of excessive bleeding or clot formation.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wang, Lee-Ho, et al. "Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis." Journal of Biological Chemistry 271.33 (1996): 19970-19975.