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Mouse Anti-Porcine Tropomyosin Receptor Kinase C (TrkC) Monoclonal Antibody

Cat. No.VD9N5

Product TypeAnimal-targeted Antibodies

Size 100ug

Product Overview

BioVenic mouse monoclonal antibody is specific for tropomyosin receptor kinase C. It is affinity purified by protein G. It can be applied to WB and Indirect ELISA assays of tropomyosin receptor kinase C.

Specifications

Application WB; Indirect ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone S1N5
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Tropomyosin Receptor Kinase C
Isotype IgG1
Immunogen Recombinant protein of tropomyosin receptor kinase C
Purification Protein G Purified
Concentration 1 mg/mL
Conjugation Unconjugated
Buffer Phosphate Buffered Saline
Physical State Liquid

Target Information

Porcine tropomyosin receptor kinase C (pTrkC) is a member of the tropomyosin receptor kinase (TRK) family, which plays a vital role in the development and maintenance of the nervous system in pigs. This receptor tyrosine kinase is activated by neurotrophins, such as brain-derived neurotrophic factor (BDNF), and is crucial for neuronal growth, differentiation, and survival. As a target for research, pTrkC is significant for understanding the molecular mechanisms underlying neuronal signaling and synaptic plasticity. It is implicated in various neural processes, including learning, memory, and pain sensation. Abnormalities in TrkC signaling have been associated with neurodegenerative diseases and developmental disorders, highlighting its potential as a therapeutic target.

Target Tropomyosin Receptor Kinase C
Target Synonym GP145 TrkC
Gene ID 397511
UniProt ID P24786

Shipping and Storage

This product is shipped with ice gel packs. Store at -80°C on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Wong, Derek, et al. "Methods for identifying patients with tropomyosin receptor kinase (TRK) fusion cancer." Pathology & Oncology Research 26 (2020): 1385-1399.
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