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Mouse Anti-Porcine Tropomyosin Receptor Kinase C (TrkC) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for tropomyosin receptor kinase C. It is affinity purified by protein G. It can be applied to WB and Indirect ELISA assays of tropomyosin receptor kinase C.
Specifications
Target Information
Porcine tropomyosin receptor kinase C (pTrkC) is a member of the tropomyosin receptor kinase (TRK) family, which plays a vital role in the development and maintenance of the nervous system in pigs. This receptor tyrosine kinase is activated by neurotrophins, such as brain-derived neurotrophic factor (BDNF), and is crucial for neuronal growth, differentiation, and survival. As a target for research, pTrkC is significant for understanding the molecular mechanisms underlying neuronal signaling and synaptic plasticity. It is implicated in various neural processes, including learning, memory, and pain sensation. Abnormalities in TrkC signaling have been associated with neurodegenerative diseases and developmental disorders, highlighting its potential as a therapeutic target.
Shipping and Storage
This product is shipped with ice gel packs. Store at -80°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wong, Derek, et al. "Methods for identifying patients with tropomyosin receptor kinase (TRK) fusion cancer." Pathology & Oncology Research 26 (2020): 1385-1399.