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Omics Solution in Animal Nutrition and Metabolism

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Genomics Solutions Proteomics Solutions Metabolomics Solutions Multi-Omics Solutions Applications Our Advantages

The development of biotechnology has provided new tools for animal nutrition and metabolism research. Omics techniques including genomics, transcriptomics, proteomics and metabolomics have wide applications in animal nutrition research applications. BioVenic has rich experience in animal nutrition and metabolism related omics research, especially in experimental design, quality control and data analysis. With our advanced instrument platforms, we are committed to providing our customers with one-stop solutions for animal nutrition and metabolism related genomics, transcriptomics, proteomics and metabolomics solutions.

Genomics Solutions for Animal Nutrition and Metabolism Study

Nutrigenomics reveals how bioactive chemicals in feed affect the nutritional metabolism of animals by altering gene expression. Our technical team pays close attention to the latest advances in nutrigenomics, including the effects of different nutrients on gene expression in animals and the effects of nutrients on gut flora. Our genomics study platform can meet your needs to study animal nutrition and metabolism at the molecular level, providing you with high-throughput genomic data. Our solution also provides biological interpretation of the data to help you understand the hidden truth of animal nutrition and metabolism.

Fig. 1 Dietary aspects in nutrigenomic studies (Nowacka-Woszuk, 2020)Fig. 1 Dietary aspects examined in nutrigenomic studies1,2.

Using high-throughput DNA sequencing and bioinformatics, we can assemble and analyze the function and structure of your animals' entire genomes. Our genome sequencing allows you to analyze genetic variation at the individual or population level, helping you discover genomic biomarkers for nutritional disorders and enabling your precision animal nutrition plan. In addition to the representative services listed below, we also offer exome sequencing, mitochondrial genome sequencing, pan-genome sequencing, and more genome sequencing solutions for researchers.

De Novo Genome Sequencing

Our de novo genome sequencing solution gives you a new way to explain animal genomic variation related to nutrition.

Single Cell Genome Sequencing

Our single-cell sequencing for animal nutrition and metabolic study provides a higher resolution to study cellular differences.

Tailored for comprehensive transcriptomic analysis, our solution identifies all transcriptome components - including mRNA and non-coding RNA (lncRNA, circRNA, and smallRNA) - within a defined nutritional environment. Using high-throughput sequencing technologies, we rapidly capture a holistic view of transcript sequences in an animal during specific nutritional states. This enables the precise study of nutritional effects on gene expression and gene structure variations, and facilitates the identification of nutrition-related molecular markers with remarkable accuracy.

The relationship between microorganisms and animals, as well as their interactions with nutrients, is a burgeoning area of interest in animal nutrition and metabolism studies. Our microbiome sequencing solution delves into the composition and diversity of microbial communities within samples. By sequencing and utilizing bioinformatics analysis of specific microbial signature sequences - such as the variable region of bacterial/archaeal 16S rRNA genes, the variable region of fungal 18S rRNA genes, or the internal transcribed spacer region of fungal ITS (Internal Transcribed Spacer)—we unlock insights into the intricate microbial landscapes present in animal systems.

Based on a high-throughput sequencing platform, we provide epigenomics sequencing service for animal nutritional studies, which can detect heritable changes in gene expression and regulations. Commonly used epigenetic sequencing methods include bisulfite sequencing (BS-seq) and ChIP-seq.

DNA Methylation Sequencing

We perform highly accurate methylation studies at the genome-wide level to build fine genome-wide DNA methylation profiles of animal nutritional samples for our customers.

ChIP-Seq

Our ChIP-Seq technology enables efficient genome-wide detection of DNA-protein interactions.

Proteomics Solutions for Animal Nutrition and Metabolism Study

  • Qualitative Proteomics Analysis

Based on LC-MS/MS shotgun technology, we offer solutions for the identification and analysis of proteins related to animal nutrition and metabolism, capable of identifying hundreds or thousands of proteins simultaneously.

  • Quantitative Proteomics

Proteomics provides a better understanding of the structure and function of the animals than genomics. Our quantitative proteomics solution measures change in animal protein expression levels across different nutritional conditions or treatments.

  • Post-Translational Modification (PTM) Proteomics

Post-translational modifications profoundly influence the biological functions and characteristics of proteins associated with animal nutrition and animal products. Leveraging our advanced proteomics research platform, we offer comprehensive solutions tailored for researchers in animal nutrition. Our services encompass investigations into phosphorylation, glycosylation, acetylation, ubiquitination, and methylation modifications. With our expert team, we deliver end-to-end services, from detection through assays to detailed analyses, to support a thorough understanding of protein modifications and their impact on animal nutritional processes.

Metabolomics Solutions for Animal Nutrition and Metabolism Study

The fluctuation in nutrient levels not only influences the proteome of animals but also induces a cascade of modifications in small molecule metabolites. BioVenic offers cutting-edge mass spectrometry (MS) and nuclear magnetic resonance (NMR) platforms, empowering animal nutrition researchers with advanced untargeted metabolomics and quantitative metabolomics solutions. With our comprehensive tools, researchers can delve into the intricate metabolic changes driven by variations in nutrients.

Multi-omics solutions (BioVenic Original)

Multi-Omics Solution for Animal Nutrition and Metabolism Study

The incorporation of multi-omics techniques has revolutionized the field of animal nutrition research by offering a wealth of data and facilitating swift, all-encompassing molecular insights into scientific inquiries. Our comprehensive platform offers a streamlined solution to leverage multi-omics methodologies. By combining various omics approaches, our platform empowers users to gain a profound understanding of animal nutrition and metabolism, going beyond surface-level analysis.

Applications of Omics in Animal Nutrition and Metabolism

Microbiome
  • Influence of nutrients on gut flora
  • Influence of feeding practices on gut flora
  • Dynamics of intestinal flora (by space, time)
  • Identification of promising feed enzyme-producing microbes
Transcriptomics
  • Feed nutrient function pathways/ molecular mechanisms
  • Transcriptomic effects of nutrients (deficiencies, excesses, etc.)
  • Mechanisms of diet on metabolic diseases
Proteomics
  • Molecular mechanisms of nutritional metabolic diseases
  • Mechanisms of nutrients on animal nutritional status
Metabolomics
  • Effect of feed additives on meat quality
  • Effects of feed additives on nutrient metabolism
  • Mechanisms of nutrition on metabolic diseases, antioxidant capacity, etc.
Multi-Omics
  • Transcriptomics+ Metabolomics: meat quality, nutrient effects on rumen, liver and other organs
  • Transcriptomics+ Microbiome: mechanism analysis of nutrients
  • Microbiome+ Metabolomics: to investigate the potential role of nutrients on microbiota and their or host metabolites
  • Microbiome+ Proteomics: to study the mechanisms of intestinal hypofunction due to nutritional deficiencies
  • and more.

Our Advantages on Animal Nutrition and Metabolism Analysis

  • Tailored to your specific research requirements, we offer customizable omics research services focused on animal nutrition and metabolism.
  • Our cutting-edge technology enables the detection of proteomes, microbiomes, metabolomes, and more across a diverse range of animal nutrition-related samples.
  • Supported by our proficient technical team, we provide an all-inclusive suite of services encompassing sample collection, assay platform selection, rigorous assay process quality control, analysis of experimental data, and comprehensive interpretation of results.

Comprising a team of passionate animal enthusiasts coupled with educational backgrounds in animal science and veterinary, our collective mission is to make meaningful contributions to the field of animal nutrition research. With our expertise, BioVenic empowers researchers with valuable insights into the intricate dynamics of animal nutrition and metabolism. Our omics solutions, which includes genomics, metabolomics, proteomics, and multi-omics solutions, can accelerate research in animal nutrition and metabolism. If you have any questions about our omics solutions in animal nutrition and metabolism, don't hesitate to contact us.

References

  1. Image retrieved from Figure 1 "Overview of dietary aspects examined in nutrigenomic studies" Joanna et al., 2020, used under [CC BY 4.0]. The title was changed to "Dietary aspects examined in nutrigenomic studies”
  2. Nowacka-Woszuk, Joanna. "Nutrigenomics in livestock-recent advances." Journal of applied genetics vol. 61,1 (2020): 93-103.
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