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Rabbit Anti-Chicken E3 Ubiquitin-Protein Ligase Parkin Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for chicken E3 ubiquitin-protein ligase parkin. It is purified by affinity chromatography. It can be applied to WB, IHC, IF and ELISA assays of chicken E3 ubiquitin-protein ligase parkin.
Specifications
Target Information
Chicken E3 Ubiquitin-Protein Ligase Parkin (PARK2) is a RING-between-RING E3 ubiquitin ligase involved in the ubiquitination pathway, mediating the degradation of specific substrates through the ubiquitin-proteasome system. It plays a crucial role in mitochondrial quality control by promoting the degradation of damaged mitochondria via mitophagy. Mutations in the Parkin gene are associated with familial Parkinson's disease, highlighting its importance in neuroprotection. Parkin is also involved in transcriptional regulation, protein degradation, and cellular stress response.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.