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Goat Anti-Swine IP-10 Polyclonal Antibody
Product Overview
O13H51 polyclonal antibody is specific for Swine IP-10, also known as CXCL10. It was purified from whole serum by affinity chromatography. It can be applied for ELISA and Western Blot (WB).
Specifications
Target Information
10 kDa interferon-gamma-induced protein (IP-10, also called CXCL10) is categorized functionally as a Th1-chemokine that is induced by IFN-γ and secreted by various cell types, such as, monocytes, neutrophils, endothelial cells, keratinocyte, fibroblasts, mesenchymal cells, dendritic cells, and astrocytes. The sequences of important regulatory elements such as the interferon-stimulated response element (ISRE), and two NF-kappaB binding elements are conserved in the proximal promoter region of swine IP-10, like other mammalian IP-10s. IP-10 plays an important role in cytotaxis of T cells and monocytes and promotes T cell adhesion to endothelial cells.
Shipping and Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at 2-8°C on receipt (up to 12 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
User Note
- DO NOT FREEZE. This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
References
- Franzoni, Giulia, et al. "Analyses of the impact of immunosuppressive cytokines on porcine macrophage responses and susceptibility to infection to African swine fever viruses." Pathogens 11.2 (2022): 166.