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Veterinary Organoid Solution

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Animal Cell 3D Culture System Development Organoid Culture System Development Organoid-on-Chip System Development Applications Why Choose Us?

Organoids are miniature "organs" induced and cultured in vitro from animal stem cells, which can partially reproduce the physiological functions of organs. As animal husbandry gradually transitions into the molecular age and the development of personalized therapies for companion animals emerges as a new research focus, organoid-related technology has started to capture the attention of researchers and has entered the stage of history. Veterinary organoids combine the advantages of two-dimensional cell in vitro culture research and animal models. They easily replicate the microenvironment and cell-to-cell interactions in the body, enabling visual detection and high-throughput screening. Additionally, they allow for the manipulation of molecular processes, such as genetic engineering. BioVenic has launched a one-stop customized solution for this cutting-edge and popular scientific research direction. From generation, characterization, and combination with microfluidic chips, to the design and optimization of the culture system, our scientific research team will support your goals and wishes to apply veterinary organoids in your projects.

Fig.1 Organoids Provide an Excellent Platform for Animal Research. (Kar, et al., 2021)Fig.1 Organoids Provide an Excellent Platform for Animal Husbandry and Veterinary Research.1,2

Animal Cell 3D Culture System Development

BioVenic has established an advanced platform for developing animal cell 3D culture systems, providing customers with one-stop services for three-dimensional cell culture. This enables the reconstruction of the spatial arrangement of animal cells in vitro. Through customized services, we offer customers more physiologically relevant information and predictive data. To meet the diverse technical needs of researchers, the platform includes optimizing and implementing scaffold systems and serum-free culture systems. BioVenic is a reliable scientific research partner for designing and executing research projects in emerging fields like artificial meat, organoids, cell therapy, and veterinary drug development.

Fig.2 In Vitro Animal Cell Culture is Transitioning from 2D to 3D. (BioVenic Original)Fig.2 Animal Cell Culture In Vitro is Transitioning from 2D to 3D.

Organoid Culture System Development

BioVenic provides customized application-based services to researchers with a need to develop organoid culture systems, addressing all technical challenges in the culture process. We are committed to providing comprehensive design and development of organoid in vitro culture systems, as well as subsequent optimization, for customers involved in the early stages of animal cell therapy and veterinary drug development. Our goal is to ensure high-quality, efficient, and reliable organoid culture system development services through standardized processes and strict quality control systems. We aim to enable users to utilize culture schemes to achieve robust growth of organoids while ensuring consistency, repeatability, and faithful reproduction of the in vivo characteristics of specific animal organs. The integrated and high-quality organoid culture technology process is a solid foundation and guarantee for the overall veterinary organoid solution.

Fig.3 Veterinary Organoid Culture Flow Chart. (BioVenic Original)Fig.3 Flow Chart of Veterinary Organoid Culture.

Organoid-on-Chip System Development

Leveraging our extensive background in animal cell biology and expertise in cutting-edge microfluidic technology, we integrate microfluidic solutions with animal cell 3D culture and organoid-related technology to create a tailored engineering platform for veterinary organoid chip design and development. The BioVenic team consistently merges expertise with creative concepts to deliver state-of-the-art, innovative, and top-notch solutions.

Applications of Organoids in Veterinary Disease Research

Organoids Species Cell Origin Purpose Significance
Intestine Feline, canine, bovine, equine, porcine, and ovine. Adult stem cells
  • Organoid transplantation
  • Inflammatory bowel disease models
  • Feline coronavirus research
  • In-depth molecular and functional characterization of intestinal organoids.
  • Establishment of companion animal disease models.
Liver Feline, canine and equine. Adult stem cells
Induced pluripotent stem cells
  • COMMD1-deficient canine model of hepatic copper accumulation
  • Feline lipidosis models
  • Some aspects of gene expression and function advance veterinary pharmacology research.
  • Provide lessons for large animal models of autologous stem cell transplantation as disease model systems.
Skin Canine Adult stem cells
  • Atopic dermatitis models
  • For disease modeling.
  • Study of transdermal drug absorption.
Neurons Canine Induced pluripotent stem cells
  • Epilepsy models
  • Narcolepsy models
  • For modeling a variety of neurological diseases.
Cancer Feline and canine Tumor cells
  • Prostate cancer models
  • Breast cancer models
  • Thyroid cancer models
  • Bladder cancer models
  • As a companion animal cancer disease model.
  • As a predictive model for drug response or therapy.

Why Choose Us?

BioVenic has a profound research and academic background in animal cytology and physiological metabolomics. We are well-versed in the physiological structure, function, and interaction of various tissues.

BioVenic utilizes cross-domain platforms to leverage microfluidic chips, high-throughput detection, animal cell culture system development, etc., to provide organoid solutions.

BioVenic comprehensively upgrades the cell biology technology platform, standardizes the basic operational processes, minimizes cell damage, and ensures the smooth and efficient implementation of the solution.

BioVenic offers a comprehensive range of tailored services for veterinary organoid research, a field with promising growth opportunities. Organoids, superior to traditional planar cultures, effectively replicate the physiological state and microenvironment of cells and tissues in animals. They are becoming increasingly popular for assessing the efficacy of veterinary drugs and modelling animal diseases. If you have any interest in veterinary organoid development, please don't hesitate to contact us for specialized solutions.

References

  1. Image retrieved from Figure 1 "Application opportunities of organoids in livestock and veterinary research." Kar et al., 2021, used under [CC BY 4.0] (https://creativecommons.org/licenses/by/4.0/). The original title was changed to "Organoids Provide an Excellent Platform for Animal Husbandry and Veterinary Research."
  2. Kar, Soumya K., et al. "Organoids: a promising new in vitro platform in livestock and veterinary research." Veterinary Research 52 (2021): 1-17.
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