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Animal Milk Metabolomics

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Background Animal Milk Non-targeted Metabolomics Analysis Services Flow Chart Applications Research Overview Why Choose Us?

Background of Animal Milk Metabolomics

BioVenic has launched customized animal milk metabolomics for scientific researchers worldwide. As a powerful tool, it enables customers to gain a comprehensive understanding of the composition and dynamic changes of metabolites in dairy products. This allows for an in-depth scientific analysis of the quality of animal colostrum and dairy products and the factors that influence animal immune acquisition at birth and dairy product quality and safety.

Background of Animal Milk Metabolomics

Milk metabolomic analysis can significantly reduce testing costs by identifying the chemical components of products determined by various biochemical processes, assessing individual animal metabolism and production levels, and analyzing breast milk composition and physiological effects. Animal milk is rich in metabolites, including essential nutrients, particularly colostrum, which plays a crucial role in the health and development of newborns. Animal milk and its derived dairy products are essential components of the human diet. Maintaining the nutritional quality and safety of dairy products has become one of the important topics in dairy research. Metabolomics is increasingly utilized in the food and nutrition fields, and research in metabolomics on animal dairy products has significantly increased in the past few years. This indicates that metabolomics has become a significant tool in milk and dairy products research.

Fig.1 Schematic Diagram of Factors Influencing the Quality of Dairy Products. (Suh, et al., 2022) Fig.1 Schematic Diagram of Factors Influencing the Quality of Dairy Products. 1

Animal Milk Non-targeted Metabolomics Analysis Services

BioVenic's non-targeted metabolomics analysis service for animal milk samples comprehensively and in-depth analyzes the levels of metabolites in milk and dairy products to understand the physiological status and milk production of the individual animals involved. The animal milk metabolome is not only a snapshot of the metabolic processes of milk-producing animals but also a powerful tool to investigate the significance of colostrum in neonatal nutrition and acquired immunity. From sample collection and processing to instrument detection and metabolomic analysis, we offer a comprehensive and high-quality one-stop solution:

At the same time, BioVenic also provides non-targeted metabolomic analysis services for blood, saliva, urine, and other animal samples.

Flow Chart of Animal Non-targeted Metabolomics Analysis Service

Fig.2 Flow Chart of Animal Non-targeted Metabolomics Analysis Service. (BioVenic Original)

Animal Milk Untargeted Metabolomics Applications

  • Metabolomics in Milk Quality

The breeds and individual differences of milk-producing animals are the primary factors that determine the quality of dairy products. Most of the metabolites in animal milk samples come from cellular activity and metabolism, which reflect the overall metabolic level and physiological state. External factors, such as the environment and feeding system, are equally important. These factors can also be effectively analyzed and presented through metabolomics testing data analysis reports. The application of metabolomics in animal health and dairy product quality evaluation brings new opportunities to livestock industries and dairy industry.

  • Metabolomics in Milk Product Quality

Assessing the nutritional quality and safety of derived dairy products, such as yogurt and cheese, through metabolite information, is another important application of animal milk metabolomics. In addition to the quality of milk, which serves as the foundation for all dairy products, various parameters and chemical factors throughout the production process are also crucial. The application of metabolomics methods, coupled with statistical modeling, can enable convenient and efficient comparative analysis of production parameters and ingredient ratios. This approach greatly accelerates the development and optimization process of dairy products.

  • Metabolomics in Animal Colostrum

Animal colostrum contains a large amount of immune and growth factors, high protein content, low fat and sugar content, 10 to 17 times the iron content of fresh milk, 3 and 10 times the vitamin D and A respectively and has unique physiological functions. Newborn mammals acquire passive immunity within the first 24 hours after birth because the permeable gastrointestinal tract allows large amounts of immunoglobulins in breast milk and colostrum to freely pass through the intestinal barrier within 24 to 48 hours after birth. Metabolomic analysis of animal colostrum is used to characterize the metabolites present in it and to establish a theoretical foundation for the nutritional needs essential for the normal growth and development of newborns.

Animal Milk Metabolomics Research Overview

Applications Directions Samples Instruments Objective
Milk Quality Genetic traits Cattle, buffalo, yak, goat, sheep, horse, and camel milk NMR
LC-MS
GC-MS
To study metabolic differences between species.
Environment Milk under various environmental conditions NMR
LC-MS
LC-QTOF-MS
To elucidate changes in metabolic levels and entry components under different environmental conditions.
Nutrition Milk from different feeding regimes NMR
LC-MS
LC-QTOF-MS
To evaluate nutritional quality and authenticity.
Status Cattle milk
Regimes
NMR
LC-MS
To find metabolite indicators.
To study metabolic alterations.
To discriminate metabolic profiles between different feeding methods.
Contamination Milk under different storage conditions
Milk contaminated with mycotoxins
LC-QTOF-MS
LC-TOF-MS
To set up metabolomics platform.
To explore photooxidation mechanisms.
Milk Product Quality Starter culture Yogurt
Cheese
NMR
GC-MS
LC-QTOF-MS
To elucidate metabolic differences from different starter cultures and their roles.
Fermentation Yogurt GC-MS
GC-IMS
To elucidate metabolic changes in yogurt at different fermentation times or under different fermentation temperatures.
Storage Yogurt
Cheese
GC-MS To identify metabolic variations during storage.
Coagulation Cheese NMR
LC-MS
To identify quality indicators for milk coagulation to produce cheese.

Why Choose Us?

Fig.3 Animal Milk Metabolomics One-Stop Services. (BioVenic Original)

Customized one-stop solution for metabolite differences and related metabolic pathway analysis in animal milk.

Fig.4 Animal Milk Metabolomics Sample Collection. (BioVenic Original)

Well-established and continuously optimized procedures for collection and pre-processing of animal emulsion samples.

Fig.5 Animal Milk Metabolomics Professional Team. (BioVenic Original)

Designed and implemented by an experienced animal metabolomics technical team.

BioVenic relies on its sophisticated biochemical testing platform and extensive experience in animal emulsion metabolomics projects to tailor service plans for scientific research projects on animal metabolism regulation and dairy biomarker development. If you are studying potential metabolic indicators and metabolic mechanisms related to the quality of animal dairy products, comparing, and analyzing genetic characteristics between milk-producing species, or investigating the impact of colostrum on neonatal nutrition and immunity, we are your reliable research partner. Feel free to contact us and inquire about animal milk metabolomics.

References

  1. Suh, Joon Hyuk. "Critical review: Metabolomics in dairy science–Evaluation of milk and milk product quality." Food Research International 154 (2022): 110984.
  2. Toral, Pablo G., et al. "Plasma and milk metabolomics in lactating sheep divergent for feed efficiency." Journal of Dairy Science 106.6 (2023): 3947-3960.
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