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Animal Digestion and Absorption Solution
Digestion and absorption of nutrients are essential for the normal physiological activities of animals. Studies of animal digestion and absorption help us to understand animal physiology, nutritional requirements, and feed digestibility and bioavailability, providing valuable insights into animal nutrition and feed development. BioVenic provides in vivo and in vitro model development, nutrient and metabolite assays, microbiological testing, and other analytical services for the study of digestion and absorption in a wide range of farm and companion animals.
One-stop Solution for Animal Digestion and Absorption
Our monogastric digestion and absorption solution is aimed at addressing the different physiological characteristics of digestion and absorption in monogastric animals such as pigs, poultry, dogs, cats, and horses. Our solutions provide one-stop services including model construction, digestion and absorption indices evaluation, feed and metabolite evaluation, etc. They can be applied in a wide range of monogastric animal nutritional studies, such as feed development, mechanism studies, biomarker discovery, health status assessment, etc.
Fermentation in monogastric animals primarily takes place in the hindgut. Numerous studies have demonstrated that the composition, structure, and function of intestinal microorganisms in these animals are significantly associated with factors such as growth performance, health indicators, and product quality. Our solutions for monogastric fermentation facilitate both in vivo and in vitro research into this process. By examining the composition and dynamics of microbial communities, microbial metabolites, and associated animal indicators during fermentation, we support research efforts aimed at understanding and optimizing fermentation in monogastric animals like pigs, chickens, dogs, cats, and horses.
Ruminants, such as cattle, goats, sheep, etc., have different digestive tract structures from those of monogastric animals. We have developed our Ruminant Digestion and Absorption Solution to address the rumen fermentation characteristics and hindgut absorption characteristics of ruminants. Our ruminant digestion and absorption solutions include the development of in vivo and in vitro models, feed and metabolite assays, ruminant digestion and absorption metrics, and rumen microbiology solutions.
The rumen hosts a diverse array of microorganisms, including bacteria, protozoa, and fungi, which play a crucial role in the digestion of feed. This vast microbial community maintains a symbiotic relationship that significantly influences the host's metabolism, making it a focal point of ruminant nutrition research. Utilizing animal experiments and artificial rumen technology, our services facilitate the exploration of rumen fermentation characteristics of feed nutrients. Through our comprehensive microbial testing, microbial metabolite analysis, feed nutrition evaluation, and animal biochemical indicator testing, we advance the understanding of ruminal microbial fermentation.
Animal Digestion and Absorption Model Development
Animal digestion and absorption models include in vivo studies using live animals and in vitro models using cells, organoids, in vitro digestion, and in vitro fermentation systems. Depending on the purpose of the study, we can help you choose the right type of model and provide one-stop service for model construction, validation, and optimization to help you conduct digestion and absorption studies in a wide range of animal species and nutrient types.
| In Vivo Models | In Vitro Models |
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Model Animals Pig Chicken Canine Feline |
Gastrointestinal Cell Models Gastrointestinal Organoid Models In Vitro Digestive Models In Vitro Fermentation Models |
Animal Digestion and Absorption Nutritional Analysis
Nutritional analysis of feed, digesta, feces, urine, etc. is a necessary step in animal digestion and absorption research. Our chemical, chromatographic, NIR, and other feed analysis platforms are capable of detecting and analyzing a wide range of nutrients (crude protein, crude fiber, crude fat, amino acids, trace elements, vitamins, etc.) and energy. This helps in the validation of experimental diet formulations and the calculation of digestibility in in vivo and in vitro animal digestion and absorption studies.
Table. 1 Comparison of wet chemistry and NIR feed analysis techniques.
| Wet chemistry | NIR | |
|---|---|---|
| Principles |
Based on chemical reactions and physical measurements, such as titration and colorimetry. |
Based on the characteristic absorption spectra of substances in the near-infrared region, predicting nutrient contents through data analysis. |
| Advantages |
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| Disadvantages |
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| Applications |
As a standard analysis method, used for developing and validating other analytical techniques. |
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Animal Digestion and Absorption Metabolites Analysis
Through physical, chemical and biological actions in the gastrointestinal tract, nutrients consumed by animals are converted into small molecule metabolites. Our metabolite testing and analysis platform provides testing services for a wide range of nutrient metabolites, gastrointestinal microbial metabolites, and animal physiological metabolites. Our assay technologies include immunological assays, chemical assays, chromatographic assays, etc. We also provide assay technology development services for specific metabolites. Our metabolomic platform provides targeted and untargeted metabolic analyzing that can provide a more comprehensive biological interpretation of your animal digestion and absorption studies and support the discovery of small molecule biomarkers.
Please check the following links for more information on our services.
Glucose, fructose, galactose, volatile fatty acids, etc. |
Amino acids, ammonia, urea, creatine, creatinine, etc. |
Fatty acids, monoglycerides, diglycerides, cholesterol, bile acids, etc. |
Nucleosides, nucleotides, purines, pyrimidines, etc. |
Short-chain fatty acids, secondary bile acids, indoles, phenols, amines, etc. |
Antioxidants, phytochemicals, xenobiotics, etc. |
Vitamin A, vitamin D, vitamin E, vitamin K, vitamin C, B vitamins, calcium, iron, zinc, magnesium. |
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Digestive Function Testing
Assessment of gastrointestinal tract digestion and absorption function is an important part of animal digestion and absorption related research, not only to help animal nutritionists study the effects of feed on normal gastrointestinal tract function, but also to help understand animal health. We offer testing services for animal digestive function that can measure digestive enzymes, gastrointestinal hormones and other indicators.
- Enzymatic Solutions for Animals
Our enzymatic solutions include determination of enzyme activity, enzymatic properties, isolation and identification of enzymes, recombinant expression, and more. These solutions not only allow the study of animals' own digestive enzymes, but also help to study microbial enzymes and develop enzymes as feed additives.
- Gastrointestinal Hormones Solutions
Gastrointestinal hormones play a role in regulating animal feeding, gastrointestinal motility, endocrinology, and more. Our gastrointestinal hormone solutions provide assays for a wide range of gastrointestinal hormones in ruminants and monogastrics, and enable the study of protein and gene expression of gastrointestinal hormones.
Gastrointestinal Absorption Function Assays
In addition to nutrient and metabolite analysis, we also offer solutions for the analysis and determination of a wide range of nutrient transport proteins. We can detect the content and expression of biomarkers such as glucose transporter proteins, amino acid transporters, fatty acid binding proteins, etc. in the gastrointestinal tract of animals, which can provide references for the study of absorption mechanisms.
Gastrointestinal Permeability/ Barrier Function Assays
The barrier function of the gastrointestinal tract plays an important role in maintaining normal digestion and absorption functions and resisting interference from foreign harmful substances. Our solutions for animal gastrointestinal permeability or barrier function include the detection and analysis of biomarkers (e.g. DAO, tight junction proteins, LPS, D-lactic acid), providing valuable insights into the digestive and absorptive function of the gastrointestinal tract.
Microbial Solution for Animal Digestion and Absorption
By leveraging our next-generation sequencing (NGS) platform, we provide comprehensive solutions for analyzing the community composition, diversity, functional prediction, and discovery of microbial biomarkers. We have extensive experience in microbial detection and analysis of various sample types, such as feces, digesta, and rumen contents, and can offer customized solutions to meet your needs.
The gut microbiota ferments feed nutrients, producing various beneficial or harmful metabolites. Our microbial metabolite analysis service can detect and analyze the short-chain fatty acids, secondary bile acids, indoles, amines, and other metabolites produced by the gut microbiota. This can help you investigate the impact of gut microbiota on animal digestion and absorption.
Workflow of Animal Digestion and Absorption Solution
Why Choose Us?
We have a complete technical service platform covering all aspects of animal digestion and absorption research, providing you with a one-stop solution.
Our services and products are specifically developed for farm animals and companion animals, ensuring the species-specificity of your research.
Our technical team has an in-depth understanding of the physiological characteristics of animal digestion and absorption, and can provide you with feasible research recommendations.
As your trusted partner in animal nutrition and feed research, BioVenic is committed to integrating our advanced technologies in animal nutrition metabolite detection, animal feed analysis, and animal gut microbiota analysis, to provide one-stop technical solutions and services for animal nutrition researchers. If you are interested in our animal digestion and absorption solutions, please feel free to contact us, and we will respond to you promptly.