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Feed Enzymes-Carbohydrases
Carbohydrases, also known as carbohydrate-active enzymes, play crucial roles in the synthesis, alterations, and breakdown of glycoconjugates, oligo- and polysaccharides. BioVenic provides comprehensive solutions for the advancement of carbohydrases as enzymes for animal feed. Our services encompass the development and refinement of carbohydrases, investigation into the application of feed carbohydrases, and the creation of animal feed carbohydrase products.
Primary Carbohydrases
Carbohydrases form a diverse enzyme group with varied functions. Noteworthy carbohydrases commonly included in animal feed formulations are outlined below:
Xylanase
Enzymes that break down xylan, integral to plant cell structures. Xylanase supplementation is prevalent in swine and poultry production to diminish intestinal viscosity and enhance nutrient absorption.
Beta-glucanase
A diverse set of enzymes catalyzing the breakdown of β-glucans. Exogenous beta-glucanases counteract negative impacts of β-glucans and maintain the natural gut microbiota.
Beta-mannanase
Major enzymes that degrade mannan, sourced from plants, animals, and microorganisms. Supplementing diets with β-mannanase, especially in high fiber or low-energy diets, offers various benefits to animals.
Amylases
Enzymes breaking down starch into glucose polymers, primarily used to boost starch digestibility in animals.
Cellulase
Microbial enzymes targeting cellulose breakdown into glucose, potentially enhancing growth performance, feed digestibility, and product quality in animals.
Pectinase
An enzyme group hydrolyzing pectic substances found in microorganisms and plants. Application in animals can enhance nutrient utilization and counteract anti-nutritional factors.
Glucose Oxidase
An oxidoreductase catalyzing the conversion of glucose to hydrogen peroxide and D-glucono-δ-lactone. It aids in managing oxidative stress, maintaining health, and fostering animal growth.
Feed Carbohydrases Development and Optimization
- Exploration of Carbohydrase Enzyme Resources
Leveraging our whole genome sequencing platform to unearth novel carbohydrase genes or gene libraries for subsequent development.
- Examination of Enzyme Properties
Offering diverse assays and services to investigate activity, stability, and specificity of carbohydrases with various substrates and catalytic processes.
- Study of Carbohydrase Catalytic Mechanisms
Through advanced research platforms, delving into enzyme-substrate binding characteristics and catalytic activity centers for a deeper understanding of enzymatic reactions.
- Enzyme Modification
Employing gene modification technologies and diverse expression systems to enhance key characteristics like thermal stability and acid resistance in carbohydrases, tailoring them for animal production.
- Fermentation Optimization
Optimizing fermentation substrates and conditions for carbohydrase-producing microorganisms to devise new strategies that boost carbohydrase yield and lower application costs in animal feed.
Carbohydrases Application Study in Feed
Variations exist in carbohydrate content across feed types. To assess feed compatibility with carbohydrases, we offer feed analysis services to ascertain carbohydrate composition and aid in developing enzyme additives tailored to specific feeds.
- In Vitro Simulated Digestion
Our Animal Nutrition and Metabolism In Vitro Model Development solution provides a simulated in vitro digestion model that replicates key aspects of the digestive systems of livestock and companion animals, such as pH levels, temperature and the presence of digestive enzymes. Through the incorporation of carbohydrases into feeds and subsequent in vitro digestion testing, we facilitate the exploration of enzyme efficacy, stability, and suitable dosage determination.
- In Vivo Animal Studies
We provide a diverse range of livestock and companion animal in vivo models for studying the impact of various carbohydrase applications as animal feed additives. These studies delve into aspects like safety, effectiveness, optimal dosage, among others. Additionally, our Animal Nutrition and Metabolism Analysis and Omics Solution in Animal Nutrition and Metabolism services aid researchers in unraveling the mechanisms through which carbohydrases operate in animal digestive systems.
Feed Carbohydrase Development
Feed carbohydrase products are typically classified as single enzymes or complex enzyme blends. Furthermore, the physical state of enzymes—such as solid, liquid, or tablet forms—can influence their application efficacy. Our services encompass the development of various feed carbohydrase products through enzymatic assays, in vivo and in vitro efficacy studies tailored for different animal species and dietary compositions.
Application Effects of Carbohydrases in Animal Feed
Numerous studies have extensively explored the use of carbohydrases as feed additives in animals. The following table highlights the application effects of select carbohydrases in various animal species.
Table. 1 Application effects of some carbohydrases in animals
| Carbohydrases | Animals | Effects |
|---|---|---|
| Xylanase | Pigs | Enhanced growth performance, improved intestinal health and immune functions. |
| Chickens | Increased body weight gain and enhanced feed conversion efficiency. | |
| Dogs | Enhanced protein digestibility in diets including DDGS. | |
| Juvenile Jian carp | Improved growth, boosted intestinal enzyme activities, and influenced intestinal microbiota balance. | |
| Beta-glucanase | Pigs | Heightened ileal starch digestibility. |
| Chickens | Reduced ileal viscosity in broilers fed wheat- and barley-based diets, correlating with lowered β-glucan molecular weight in the digesta. | |
| Common carp | Potential benefits in aquafeed based on barley, supporting fish health and potentially serving as an immunity stimulant and supplementary measure for health support. | |
| Beta-mannanase | Pigs | Enhanced growth in weanling and growing-finishing pigs, with minimal impact on nutrient digestibility. |
| Chickens | Promoted egg weight in commercial layers during early production stages, increased egg production, notably delaying post-peak productivity decline. | |
| Dogs | Improved digestibility and metabolizable energy content in diets containing soybean meal. | |
| Amylases | Pigs | Improved digestibility and meat protein content. |
| Chickens | Varied effects on broilers based on amylase sources and concentrations. | |
| Cellulase | Pigs | Beneficial effects on sows by reducing post-weaning back fat thickness loss and enhancing nutrient digestibility, improving piglet average daily gain. |
| Pectinase | Pigs | Enhanced pig performance without adverse health effects when high soybean meal diets were fed. |
| Glucose Oxidase | Pigs | Enhanced growth performance, increased growth-related hormone levels, and improved fecal microflora in growing piglets. |
| Chickens | Boosted broiler growth by enhancing gut digestion and nutrient absorption, potentially through improved enzyme activity and enhanced beneficial bacterial populations. |
Animal Feed Carbohydrases Development Workflow
Why Choose Us?
Our seasoned research team specializes in animal nutrition and feed carbohydrase development, offering customized solutions aligned with your specific research requirements
Utilizing our in vivo and in vitro animal models, we empower animal nutrition researchers to delve into the impact of enzymes on distinct animal species, laying a theoretical foundation for practical applications.
By leveraging a range of internal and external resources, we excel at customizing solutions that precisely match our customers' research demands.
The advancement of feed carbohydrate enzymes plays a vital role in enhancing animal digestibility, production efficiency, and overall health. BioVenic's all-encompassing solutions aim to streamline the development of feed carbohydrate enzymes, offering a seamless service that covers the spectrum. Our services not only facilitate the creation of high-performance feed carbohydrate enzymes but also support in-depth in vivo and in vitro application studies, fostering the evolution of enzyme products. Should you seek to develop carbohydrate enzymes as animal feed additives, contact us. We eagerly await the opportunity to grasp your research requirements and provide an apt solution.