CRISPR Genome Editing in Precision Animal Breeding

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CRISPR Genome Editing in Precision Animal Breeding

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Precision genome editing based on CRISPR system is accelerating animal breeding research in innovative and revolutionary ways, including changing the traits of farmed animals to improve productivity, health and welfare. BioVenic, with extensive practical experience and a professional scientific research platform, is committed to delivering exceptional quality services of genome editing for precision animal breeding research and comprehensive customization services for gene editing tools, covering the entire process of using the CRISPR system. Our goal is to help you harness the power of the CRISPR system to reduce the workload of genome editing and break through the limitations of animal genetic modification.

One-Stop CRISPR Solution in Precision Animal Breeding

BioVenic introduces one-stop services for animal genome editing, providing mature and professional technical support for customers who have research needs for precise animal breeding. BioVenic also provides customized CRISPR genome knockout library services for multi-latitude genetic screening of farmed animals, which can be used to explore the molecular mechanisms of key traits and provide an efficient solution for the functional identification of target genes. You can get access via the following links.

Fig.1 Flowchart of Genome Editing Processes in Farm Animals. Fig.1 Schematic Diagram of Gene Editing in Livestock Animals^1,2.

Featured CRISPR Services in Precision Animal Breeding

CRISPR Genome Knockout

Customize farmed animal genome editing to meet your specific research requirements using CRISPR technology for stable and permanent gene knockout.

CRISPR Genome Knock-in

Gene knock-in is an important gene editing technology to introduce an exogenous gene or DNA fragments into the genome and transmit to the next generation. With years of experience and professional knowledge, we provide reliable custom gene editing services for farmed animal genome knock-in research program.

Base Editing

Base editors (BEs) enable precise single-base substitution in DNA or RNA by combining the CRISPR system with an individual deaminase, without generating a DNA double-strand break (DSB) or requiring donor DNA templates. We specialize in offering base editing research services to achieve precise and safe genome editing in animal breeding research.

Prime Editing

Prime-editors (PEs) are the latest addition to the CRISPR genome-engineering toolkit, expanding the capabilities of donor-free precision DNA editing to not only all transition and transversion mutations but also small insertion and deletion mutations. We offer more precise targeted editing to for precision animal breeding research requirements.

Point Mutation Introduction

When you need to perform a small amount of base exchange within the target gene at the target site, we will design a strategy for nuclease-mediated point mutation based on your specific research requirement to improve animal production, animal overall health and welfare

Comparison of Applications and Advantages of CRISPR Gene Editing Services

Services	Applications	Advantages
CRISPR Knockout / Knock-in	Permanent knockout or knock-in editing of the genome.	Short cycle. High efficiency. Multiple edits.
Base Editing	Single-base substitution in DNA or RNA.	Independent of DSBs and donor DNA. High efficiency, precision, and safety.
Prime Editing	Transition, transversion, small insertion and deletion mutations.	Less stringent PAM requirements. Wide precision editing scope.
Point Mutation	Minor base exchanges.	Mature and simple process.

Applications of Genome Modification in Animals Breeding

Applications	Animal Health	Animal Productivity	Animal Welfare
Trait Improvements	Disease resistance.	Meat production improvement. Meat quality improvement. Milk modification of beta-lactoglobulin-free. Cashmere yield improvement. Increased growth rate.	Hornlessness. Mutation correction for recessive diseases. Heat tolerance improvement. Sterility.

Why Choose Us?

Customize highly specific gene editing services according to individual needs.

Comprehensive CRISPR solutions for genome engineering in precision animal breeding research.

Secure, efficient, and professional execution.

Accurate and no random mutation-free delivery results.

Technical support to simplify gene editing for your research.

With a professional scientific research team and a rigorous service attitude, BioVenic will be the best partner for your scientific research committed to launching comprehensive and high-quality services. If you have any research needs for gene editing for precise animal breeding, get in touch with BioVenic for further details.

References

Perisse, Iuri Viotti, et al. "Improvements in gene editing technology boost its applications in livestock" Frontiers in genetics 11 (2021): 614688.
Image retrieved from Figure 2 "Schematic summary of CRISPR/Cas9 gene editing using either zygote micromanipulation (electroporation or microinjection) or somatic cell nuclear transfer (SCNT) for generation of livestock animals for various applications". Tait-Burkard, Christine, et al., 2018, used under CC BY 4.0. The original image was modified by changing title to "Schematic Diagram of Gene Editing in Livestock Animals".