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Recombinant Subunit Veterinary Vaccine Development
Subunit vaccines are made from parts of pathogens rather than whole organisms, so they do not contain any live pathogens. It contains only the necessary antigens and not all the other molecules that make up the microorganism, and the likelihood of adverse reactions is very low. In order to circumvent the safety risks and low immunogenicity associated with inactivated or attenuated vaccines based on whole-cell structures, BioVenic offers recombinant subunit veterinary vaccine development services based on multiple technology platforms., enabling discovery and development of proteins, peptides, or polysaccharides for veterinary vaccines.
Recombinant Subunit Veterinary Vaccine Development Platforms
Recombinant subunit veterinary vaccines are classified into various types for different antigenic components. From protein to polysaccharide, and from bacteria to viruses, BioVenic has established a variety of technology platforms for the development of veterinary recombinant subunit vaccines.
| Platforms | Description |
|---|---|
| Recombinant Protein Subunit Veterinary Vaccine | Specific proteins isolated from viral or bacterial pathogens, made using living organisms such as bacteria and yeast. |
| Synthetic Peptide Subunit Veterinary Vaccine | Short peptides were synthesized artificially from amino acid sequences rich in important antigenic epitopes in the protective antigen genes of pathogens, ligated into appropriate vectors, and then added with adjuvants. |
| Carbohydrate-based Subunit Veterinary Vaccine | Carbohydrate structures decorate the surface of pathogens and can be potential targets for vaccine design, most vaccines against bacterial infections are carbohydrate vaccines. |
| Conjugate Veterinary Vaccine | Combining a weak antigen with a strong antigen as a carrier causes the immune system to respond more strongly to the weak antigen. |
Our Services
Recombinant Protein Customization
BioVenic provides advanced recombinant protein production platforms covering a wide range of host cells, including mammalian cells, insect cells, bacteria, yeast, to ensure that we can customize protein production for various of veterinary-related antigens. Through sophisticated protein expression, protein purification, protein characterization, and quality control, we help customize recombinant protein products with high purity and stability for veterinary vaccine development.
| Recombinant Protein Expression Systems | Protein Purification |
|---|---|
|
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Fig.1 Recombinant protein expression and common host systems. (BioVenic Original)
Peptide Synthesis
BioVenic provides high-quality peptide synthesis services and customized peptide samples for synthetic peptide veterinary vaccine development. Our peptide synthesis process is precisely designed and optimized to ensure the synthesis of high-purity, high-quality samples of multiple types of peptides.
Comprehensive Service Types
- Desalting.
- Aliquoting.
- Lyophilization.
- Solubility Test.
High Purity
- Purity determination with SDS-PAGE.
- Achieve 70% to >98% purity.
Customized Synthetic Length
- Up to 200 amino acids.
Tailored Quantity
- Milligrams to kilograms.
- From lab-scale to large-scale.
Peptide Conjugation and Modification
- Amino acid substitution.
- Terminal modification.
- Phosphorylation.
- Glycosylation.
- Fluorescent labeling.
- Biotin labeling.
Guaranteed Quality Control
- LC-MS
- HPLC-MS
Carrier Coupling and Conjugation
Effective conjugation strategies are essential to enhance the immunogenicity of recombinant subunit veterinary vaccines. Precise coupling of protein subunits, peptides or polysaccharides to carrier proteins ensures immunogen stability and potency. As your trusted partner, BioVenic offers a wide range of reagents for cross-linking, immobilization, modification and labeling of proteins and antigenic components. We possess experience and expertise to provide you with high-quality reagents and technical support to help you succeed in veterinary vaccine development.
Recombinant Subunit Veterinary Vaccine Development Services
Recombinant subunit veterinary vaccines contain only the antigenic portion of pathogens, which ensures a high degree of safety, but the manufacturing process is complex, and because of their low immunogenicity, they require adjuvants addition and additional injections. BioVenic offers in vitro and in vivo assessments of recombinant subunit vaccines, as well as formulation development services, to ensure their safety while still possessing sufficient immunogenicity. We also have extensive experience in the manufacture of antigenic components such as proteins and peptides, as well as stringent quality control measures to ensure the smooth development and production of your vaccines.
Why Choose Us?
We offer a wide range of services for the development of recombinant subunit vaccines targeting potetial livestock, poultry, companion animals, aquaculture species and more.
We guarantee the supply of proteins and peptides with high purity, precision and customization.
We have established technological platforms for modification and coupling services required.
Short delivery times improve the efficiency of your recombinant subunit vaccine development.
By choosing BioVenic, you are not only choosing quality technology and expertise, but also choosing a passionate and innovative team. Contact us and let's work together to promote the innovative development of recombinant subunit veterinary vaccines and make greater contributions to animal health for livestock, poultry, companion animals, aquaculture species and more.