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Recombinant Protein Subunit Veterinary Vaccine Development
Recombinant protein subunit veterinary vaccines are composed of specific protein antigens including toxoid that can be synthesized in different expression systems outside their natural hosts. These systems may include bacteria, yeast, insect cells, and mammalian cells, chosen based on the specific antigen being produced. BioVenic provides encompassing services for recombinant subunit veterinary vaccine development, from expression vector construction to recombinant protein customization.
Our Services
Expression Vector Construction
The construction of expression vectors is a pivotal stage in the production of recombinant proteins. BioVenic offers expression vector construction services tailored to bolster the creation of recombinant subunit veterinary vaccines. Our expertise lies in crafting efficient expression vectors that guarantee stable and substantial yields of the desired antigenic proteins within your chosen expression system. Regardless of the scope of your project, we are dedicated to delivering a personalized expression vector construction solution that aligns precisely with your unique requirements.
Recombinant Protein Expression
BioVenic provides cutting-edge recombinant protein production platforms that cover a wide range of host cells, including mammalian and insect cells. This versatility enables us to customize protein production to suit a variety of antigens. Through meticulous process management and stringent quality assurance protocols, we consistently deliver recombinant protein products characterized by exceptional purity and stability.
Recombinant Protein Expression Platforms
Recombinant proteins are made by cloning the DNA sequence of a target gene into an expression vector and then transforming it into a host cell for expression. A major consideration in the production of recombinant proteins is the choice of expression system. BioVenic has a variety of recombinant protein expression systems, to provide customers with high-quality recombinant proteins to meet different needs.
| Expression Systems | Advantages | Limitations |
|---|---|---|
| Bacteria |
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| Yeast |
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| Insect Cell |
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| Mammalian Cell |
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Protein Purification
Given the intricate nature of proteins, protein purification is challenging and requires careful selection of purification techniques based on the specific properties of the protein in question. BioVenic provides a variety of protein purification methods and is dedicated to providing you with high-purity target proteins for recombinant protein subunit veterinary vaccine development.
| Affinity chromatography | Size exclusion chromatography |
|---|---|
| A specific tag is introduced into the target protein to selectively capture the target protein in subsequent purification steps. BioVenic recommends different purification tags for different proteins according to the characteristics of proteins and requirements. Commonly used tags are His, GST, MBP, Flag, and so on. | Size exclusion chromatography separates biomolecules based on size differences and is a non-affinity separation method that does not depend on specific interactions of the molecules, such as charge or affinity. |
| Ion exchange chromatography | Hydrophobic interaction chromatography |
| Ion exchange chromatography is based on the charged nature of molecules and usually involves a separation column filled with a resin or medium containing an ion exchange function. | Hydrophobic interaction chromatography is based on the principle that hydrophobic regions in biomolecules interact with a separation column filled with a hydrophobic medium. |
Recombinant Protein Subunit Veterinary Vaccine Development Services
Recombinant protein subunit veterinary vaccines have a high degree of safety due to their use of proteins as antigens. On the other hand, the use of proteins as immunogens alone may not stimulate animals to produce a strong immune response, making lower immunization efficiency. BioVenic provides vaccine formulation development services to supplement your protein antigen with appropriate vaccine adjuvants and other excipients. We then evaluate the safety and immunogenicity of vaccines and implement stringent quality control throughout the whole development process.
Why Choose Us?
One-stop service from gene design to protein preparation.
Development of various high expression vectors and strains.
Customized service for high purity proteins from milligrams to kilograms.
BioVenic has established advanced technological platforms for the efficient synthesis and expression of specific proteins related to animal pathogens, providing reliable support for personalized animal immunoprotection. If you have ideas for developing recombinant protein subunit veterinary vaccines, please contact us now for the in-depth partnership.