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Animal Cell Metabolomics
Animal Cell Metabolomics Services
Non-targeted animal cell metabolomics qualitatively describes the overall outcomes of intracellular and extracellular metabolic regulation, making it a valuable complement to functional genomics. It fully reflects the response of biological systems to genetic factors or external environmental changes through comprehensive and intuitive data. Compared to other omics analyses, metabolomics provides the most rapid and dynamic information about cellular functions, creating a unique fingerprint for each individual cell. Cellular metabolomics has been used to study cell physiology and pathology, pharmacokinetic monitoring, and food histology. BioVenic offers customized animal cell metabolomics solutions to scientific researchers studying cellular life activities, energy production, cell signaling, growth, differentiation, and other topics and directions related to cell function and health. Our aim is to expedite the progress of their projects.
Fig.1 Schematic Diagram of Single Cell Metabolomics Analysis. 1
Animal Cell Metabolomics Services
- Cell Sample Preparation and Extraction
We offer customers sample processing and separation services in cellular metabolomics analysis to assist them in successfully overcoming this challenging step. BioVenic's customized services enable the extraction of complex and variable metabolites from cells, even within limited volumes. BioVenic already possesses high-magnification microscopes for cell monitoring and mechanical systems for precise control of sample movement. Additionally, we have developed mature and effective extraction and desorption technology processes for obtaining cell contents. This ensures the stable preservation of comprehensive metabolite information within cells, significantly enhancing the sensitivity of metabolomics detection and the reproducibility and dependability of data.
- Metabolite Detection
The development of BioVenic's powerful metabolomics analysis and detection platform has greatly advanced various applications of cell culture in scientific research and has become a valuable tool for customers to gain a comprehensive understanding of animal cell metabolism. We combine NMR, GC, and LC with MS detection methods to provide customized solutions for metabolomics analysis. These solutions effectively characterize intracellular metabolic samples, allowing us to reflect the physiological state of cells. At the same time, we have established a newer UPLC-MS system for separating complex samples to monitor cell growth, metabolism, signal transduction, and other cellular activities in their physiological state.
- Data Analysis
We offer a variety of data analysis services, which include preprocessing of analysis results, univariate and multivariate analysis, analysis of biological diversity, identification of biomarkers, and pathway analysis. According to customers' specific scientific research needs, BioVenic utilizes traditional statistics and digital modeling to offer high-precision and in-depth advanced data analysis services.
Flow Chart of Animal Non-targeted Metabolomics Analysis Service
Animal Cell Metabolomic Analysis Applications
| Animal Disease Diagnosis | Pathological changes caused by animal diseases will correspondingly affect alterations in intracellular metabolites. Animal cell metabolomics can identify biomarkers or known/unknown metabolic pathways related to disease states by analyzing and detecting animal cells under pathological conditions. This process provides a theoretical basis for diagnosing animal diseases. |
| Veterinary Drug R&D | Metabolomics conducts systematic research on small molecule metabolites involved in the biochemical reactions of animal cells. The study of cellular metabolomics can directly reflect the changes in phenotype when drugs act. Therefore, it can be utilized to elucidate the mechanism of action of veterinary drugs and provide a framework for drug research and development. |
| Culture Media Development | The cultural environment affects the metabolic activity of animal cells. The microenvironment crucial for cell growth primarily includes glucose, oxygen, and other growth factors. When the surrounding environment changes, the metabolites in the cells also change accordingly. Cellular metabolomics can be used to analyze and monitor the effects of culture medium components. |
| Toxicity Evaluation | It is of great significance to evaluate the cytotoxicity of compounds using metabolomics technology. The research and measurement results can offer early warnings and safeguard livestock from the dangers of chemical substances in the farm environment. |
Why Choose Us?
Metabolomic analysis of animal cells to support multiple scientific research purposes.
Experienced technical team for intracellular metabolite extraction and pretreatment.
Advanced data analysis services highly customized according to customer needs.
The animal cell metabolomics analysis technology that BioVenic provides to our customers reveals information about precise metabolic pathways and processes within living cells. This is achieved by examining and identifying collections of endogenous biochemical reaction products. These metabolic processes are directly or indirectly involved in various aspects of cellular function. If you are conducting research related to cell biology, intracellular veterinary drug metabolism, cell engineering and bioengineering, cytotoxicity, or the impact of cells on the environment, please contact us to customize animal cell metabolomics solutions.
References
- Liu, Renmeng, and Zhibo Yang. "Single cell metabolomics using mass spectrometry: Techniques and data analysis." Analytica chimica acta 1143 (2021): 124-134.
- Čuperlović-Culf, Miroslava, et al. "Cell culture metabolomics: applications and future directions." Drug discovery today 15.15-16 (2010): 610-621.