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Animal/Insect Venom Metabolomics
Venoms are complex, yet underexplored, bioactive compounds that have roles and values beyond aiding animals or insects in killing their prey. Venom contains a variety of proteins, peptides, and other small molecule metabolites. The active metabolic components in the venom samples have a variety of biological functions, and some possess beneficial medicinal properties. BioVenic has recently introduced personalized analysis services for animal and insect venom metabolomics. These services aim to assist scientific researchers in utilizing state-of-the-art high-throughput detection tools and conducting comprehensive data analysis. The goal is to facilitate the study of the composition, biological effects, structure, and activity of toxins, as well as the biological information associated with venoms.
Fig.1 Schematic Diagram of Metabolic Composition Analysis for Snake Venoms. 1
Animal/Insect Venom Metabolomics Services
- Sample Collection and Preparation
The collection, storage, and preparation of toxic secretions and venom samples are the initial and critical steps for metabolomic analysis. BioVenic processes samples obtained through direct acquisition or electrical stimulation using strict standardized protocols to ensure the integrity and high quality of the metabolic components of venoms and toxins.
- Metabolite Detection
BioVenic has a variety of biochemical detection platforms, including NMR, LC, GC, and multiple detection solutions combined with MS to ensure that the signals detected in animal and insect venom samples can be reliably identified.
- Data Acquisition
The application of a large spectral database built in-house by BioVenic increases the number of metabolites identified in analyzed samples. At the same time, after strict quality control of all test data, high-throughput data analysis and modeling tools are used for statistical analysis.
- Bioinformatics Analysis
BioVenic leverages extensive project experience in animal metabolomics to conduct comprehensive biological analysis of venoms and toxic secretions. This analysis aims to enhance customers' scientific research on the underlying biological mechanisms responsible for the presence of specific metabolites in the venoms or poisons being studied.
Flow Chart of Animal Non-targeted Metabolomics Analysis Service
Animal Venom Non-targeted Metabolomics Applications
| Direction | Application |
|---|---|
| Venom Active Ingredient Analysis | Through non-targeted metabolomic detection and analysis of venom samples from animals and insects, identifying various active components in venom forms the molecular basis for gaining further insights into the toxicity of specific venoms. At the same time, some active molecules in the venom have unique medicinal value and are also the focus of researchers. |
| Venom Toxic Effect Analysis | The toxic effects of animal venoms are often caused by the interaction of multiple biomolecules that affect metabolism. Metabolomics analysis can provide a comprehensive understanding of the metabolic network of venom and explore the mechanisms related to toxicology. |
| Toxicology Therapy Development | Animal metabolomics offers scientific methods for differentially analyzing venom samples from various species, populations, and regions. This lays the groundwork for developing targeted therapies for animal poisoning. |
Why Choose Us?
Strictly standardized animal and insect venom sample processing procedures to achieve stable and repeatable data.
The diversified and advanced chromatography and mass spectrometry joint detection platform ensures high coverage of small molecule metabolites in venom samples.
High-throughput professional data statistical classification tools and bioinformatics analysis related to animal metabolism.
Comprehensive customized animal or insect venom and toxic secretion metabolomic solutions.
BioVenic utilizes standardized metabolomics tools to comprehensively detect and analyze samples of animal and insect venom. Untargeted metabolomics, which utilizes biochemical assays such as LC-MS, NMR, HPLC-MS, etc., offers customers a comprehensive and extensive analysis of the low molecular weight components found in venoms and poisons. We are committed to becoming a reliable partner for scientific researchers conducting analysis of venom components and biological activities, anti-toxic research, biodiversity, and evolution research. Please contact us for more details on how to utilize metabolomics of venoms and toxicants as a research tool that is still in its infancy.
References
- Alonso, Luis L., et al. "Metabolome-Based Classification of Snake Venoms by Bioinformatic Tools." Toxins 15.2 (2023): 161.
- Klupczynska, Agnieszka, et al. "Application of metabolomic tools for studying low molecular-weight fraction of animal venoms and poisons." Toxins 10.8 (2018): 306.