Custom Animal Stable Cell Line

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Custom Animal Stable Cell Line

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Flow Chart of Animal Stable Cell Line Development Overexpression Cell Line Development Knockout Cell Line Development Knock-in Cell Line Development Knockdown Cell Line Development Reporter Cell Line Development Custom Animal Stable Cell Line Development Services Why Choose Us?

With its extensive expertise in animal cell-related products and services, BioVenic has developed a range of services for constructing stable animal cell lines for research purposes. We have a comprehensive technology platform for molecular biology and cell biology, along with a team of experts experienced in working with various animal cell lines. We are also proficient in cutting-edge technologies related to animal genome editing, providing one-stop solutions for gene knockout, knock-in, knockdown, precise insertion, and overexpression of reporter genes for your target cell lines. Our experimental and expert teams are committed to delivering a high-quality service experience to our customers. We strive for efficient and stable delivery results, maintain frequent communication, and offer reliable professional technical support.

Flow Chart of Animal Stable Cell Line Development

Fig.1 Animal Stable Cell Line Development. (BioVenic Original)

Animal Overexpression Cell Line Development

BioVenic provides personalized services for creating animal overexpression cell lines. Our team focuses on achieving the overexpression of various target genes in multiple cell types, including those that are challenging to transfect. Through advanced transfection technology or viral packaging methods, BioVenic has successfully established numerous stable animal cell lines that overexpress target genes.

Animal Knockout Cell Line Development

BioVenic has introduced a comprehensive solution for custom-made animal knockout stable cell lines, enabling the permanent knockout of target genes in cell lines effectively. Our technical team is proficient in various gene editing methods, combined with a low-toxicity RNP delivery system, to deliver editing elements directly into the target cell line. This approach enables precise cleavage of the target DNA sequence. Based on the specific needs of scientific researchers and the characteristics of target genes and cell lines, we offer efficient and stable experimental designs for constructing animal knockout cell lines.

Animal Knock-in Cell Line Development

BioVenic assists customers in inserting foreign gene fragments into desired locations in the animal genome to create stable knock-in cell lines. Our customized protocol considers the length of the gene knock-in fragment, knock-in efficiency, and variations in editing difficulty among different cell lines to enhance success rates. We consistently refine the technical aspects of the process. Our solutions undergo multiple quality controls and repeated verifications before delivering results to ensure high-quality services.

Animal Knockdown Cell Line Development

BioVenic has developed comprehensive solutions for designing and constructing animal knockdown cell lines to silence various target genes in cells from different sources for scientific research purposes. Our technicians have mastered a variety of animal cell transfection methods, particularly the shRNA system. This system can effectively and durably inhibit gene expression and reduce target mRNA levels over an extended period. Our rigorous quality control and screening systems also guarantee the source of reliable and stable cell lines for gene knockdown, accompanied by relevant data and bioinformatics reporting.

Animal Reporter Cell Line Development

BioVenic specializes in researching in vitro reporter systems for animal cells and offers customized services for developing animal reporter cell lines. We utilize the animal genome editing platform to insert the reporter gene into the genome or even overexpress it to achieve cell luminescence imaging or transmit reporter signals through enzymatic reactions. We have expertise in a variety of reporter genes and reporter systems suitable for animal cells, various cell transfection methods, and state-of-the-art animal genome editing technologies. We are dedicated to offering customers high-quality, efficient one-stop solutions.

Custom Animal Stable Cell Line Development Services

CRISPR Genome Editing Technology

BioVenic enables precise animal genome editing through a comprehensive technology platform based on the CRISPR system. We are advancing animal genetic and metabolic research in innovative and revolutionary ways to achieve goals such as enhancing traits in farm animals to improve productivity, health, and welfare.
We are committed to providing high-quality genome knockout, knock-in, point mutation services, and comprehensive design and synthesis of gene editing tools to establish diverse and stable animal cell lines. Our goal is to assist you in leveraging the power of the CRISPR system to streamline genome editing, surpass the constraints of animal genetic modification, and acquire dependable and consistent cell lines.

RNA Interference (RNAi) Technology

RNA interference (RNAi) technology services utilize RNA molecules to suppress gene expression and achieve knockdown of target genes in animal genomes. RNAi technology can be applied in various scientific research projects, such as gene function exploration, veterinary drug development, and animal disease metabolism research.
Compared with transient silencing, achieving permanent knockdown can be done by stably integrating shRNA into the cell genome, eliminating the need to transfect cells multiple times. BioVenic's shRNA synthesis and design services focus exclusively on the viral and plasmid construction of shRNA for entire animal genomes. We used structurally optimized shRNA designs of different lengths to develop shRNA expression constructs with high knockdown efficiency and minimal off-target effects.
Our RNAi technology can achieve high-level expression of shRNA and efficiently support customers in completing shRNA design and synthesis, vector construction, transfection, mRNA expression, and downstream protein expression verification services.

Why Choose Us?

Comprehensive Solutions

Our customized services comprehensively address project requirements concerning animal stable cell lines and effectively fulfill personalized design and implementation needs.

Standardized Construction System

Our laboratory team has established standardized technical procedures for each type of stable cell line.

Rigorous Testing and Verification

Our project results undergo multiple high-standard quality inspections and appraisals before delivery, ensuring both safety and scientific value.

BioVenic utilizes its animal cell line culture and detection platform, animal genome editing platform, and high-throughput sequencing platform to generate stable monoclonal cell lines for scientific research purposes. We are your reliable partner in research areas such as veterinary drug screening and development, technical cell improvement and evaluation, and animal disease model research and establishment. Don't hesitate to contact us to inquire about our stable cell line establishment solution!