Animal Primary Cell Solution

Animal primary cells are widely used in molecular biology, cell biology, veterinary drug development and basic research in veterinary science. Compared to passaged cells and cell lines, primary cells are isolated from fresh animal tissues and organs and are closer to their natural state. They retain most of the original genome of the animal cells and have unique advantages for in vitro research. BioVenic offers a range of primary animal cell products to meet the experimental needs of scientific researchers worldwide. In addition, we offer bespoke, high quality animal primary cell development services to meet specific research needs. Our animal primary cell services have a comprehensive and mature technical process that includes isolation, culture, identification and quality control. These processes minimize the risk of foreign cell contamination and ensure cell quality across batches.

Animal Primary Cell Products

Fig.1 Marine Fish Primary Hepatocytes under Inverted Light Microscope.^1,2

Animal Primary Cell Isolation

BioVenic offers personalized animal primary cell isolation services tailored to the specific scientific research needs of researchers. Our technical team isolates and produces high purity and highly active primary cells from fresh animal tissues. We offer a variety of techniques for animal primary cell isolation, including suspension centrifugation, enzymatic digestion and density gradient centrifugation. We have continuously optimized the experimental conditions for primary cell isolation during long-term animal cell research. Delivered cell products undergo multiple stringent quality controls and support the expression of a variety of tissue cell-specific markers for characterization and identification.

Animal Primary Cell Culture

BioVenic provides customized animal primary cell culture solutions to assist researchers in promoting cell growth, improving cell viability, preserving cell-specific phenotypes and facilitating the seamless progress of scientific research projects. Our technical department develops specialized culture systems for various types of animal primary cell products to meet your needs. After careful preparation, optimization, sterility and quality testing, we provide isolated cells with an excellent growth environment for in vitro proliferation. We offer this service to facilitate our customers' research in animal physiology, pathology and veterinary drug development.

Animal Primary Cell Characterization

BioVenic provides identification and characterization services for primary cell products derived from fresh animal tissues and organs to characterize primary animal cells. The animal primary cell characterization solution primarily performs a comprehensive and in-depth analysis of animal cells from various perspectives, including morphology, cell source, specific function, and immunogenicity. Our technical team ensures the purity and cell type of primary cells through comprehensive identification and characterization.

Animal Primary Cell Immortalization

Primary animal cells often stop proliferating, enter a state of senescence and eventually die after a limited number of passages. Immortalized cells are derived from primary cells. Exogenous genes are introduced into target cells by gene transfection, thus overcoming the limited number of passages of animal primary cells and increasing their scientific research value when cultured in vitro. BioVenic has developed a sophisticated animal cell immortalization service that immortalizes animal primary cells to enable continuous proliferation when cultured in vitro, ensuring consistency between cell passages.

Advantages of Using Primary Animal Cells

• The use of primary cells helps to avoid many of the ethical controversies associated with animal experimentation. Research using primary animal cells closely mimics the conditions under which cells are studied in animals.
• The use of primary animal cells provides more relevant results than cell lines. Pre-screened primary cells are excellent models that closely mimic in vivo signaling.
• Animal primary cells are cost-effective because they help reduce the cost of individual animals needed for in vivo studies.

Why Choose Us?

BioVenic integrates leading researchers in animal physiology and cell biology to provide global customers with diverse and customizable primary cell development strategies. These strategies are designed to provide primary cells for animal physiology research and veterinary disease studies. Backed by extensive laboratory experience, our team of experts specializes in optimizing cell separation solutions and matching cell identification and characterization methods to ensure the quality of our services and the animal primary cells supplied. If you are interested in our animal primary cell solutions, please contact us to discuss your research plan.

References

1. Image retrieved from Figure 3 "Culture of S. aurata primary hepatocytes isolated by pancreatin digestion with modifications (A) and after incubation in poly-L lysine-coated plates up to 24 (B), 48 (C), and 72 h (D)." Figueiredo et al., 2021, used under [CC BY 4.0] (https://creativecommons.org/licenses/by/4.0/). The original image was modified by removing the A, B, C, and D in the image, and the title was changed to "Marine Fish Primary Hepatocytes under Inverted Light Microscope."
2. Figueiredo, Neusa, et al. "Marine fish primary hepatocyte isolation and culture: new insights to enzymatic dissociation pancreatin digestion." International Journal of Environmental Research and Public Health 18.4 (2021): 1380.