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Veterinary Therapeutic Protein and Peptide Basic Property Analysis

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Overview Basic Property Analysis Services Service Workflow Why Choose Us?

The basic property analysis service is applied to determine the basic physical and chemical properties of veterinary therapeutic proteins and peptides in preclinical research, such as solubility, melting point, viscosity, and charge heterogeneity. By integrating various analytical techniques, such as dynamic light scattering, isoelectric focusing, and capillary electrophoresis. BioVenic provides comprehensive property analysis services for veterinary therapeutic proteins and peptides, helping to ensure the quality and performance of veterinary therapeutic proteins and peptides.

Protein and Peptide Basic Property Analysis Overview

The basic property of protein and peptide determination involves both physical property and chemical properties in our service. The physical properties of these include stability, molecular weight, solubility, melting point, and viscosity, which can provide crucial information on the behavior and functionality of proteins and peptides under various conditions. In terms of the chemical properties of proteins and peptides, our service provides a detailed analysis of charge heterogeneity, isoelectric point, and extinction coefficient. BioVenic offers a comprehensive suite of services designed to thoroughly characterize proteins and peptides, thereby assisting our clients in the preclinical research, development, and application of these therapeutic biomolecules.

Fig.1 An overview of the fundamental property analysis for veterinary therapeutic proteins and peptides. (BioVenic Original)Fig.1 The overview of basic property analysis of veterinary therapeutic proteins and peptides. (BioVenic Original)

Protein and Peptide Basic Property Analysis Services

Protein and peptide basic property analysis is essential for their identification and characterization, playing a pivotal role in enhancing their efficacy and quality. At BioVenic, we offer a tailored and comprehensive solution for determining basic properties, encompassing both physical and chemical aspects. This holistic approach ensures precise control over the quality and performance of proteins and peptides, catering to the specific needs of our clients for animal health.

  • Physical Property Analysis
Description Services
Molecular Weight Refers to the mass of a protein or peptide, typically expressed in Daltons (Da).
  • Measure molecular weight using techniques like mass spectrometry, gel electrophoresis, and size exclusion chromatography (SEC) to aid in protein and peptide design and quality control.
Stability Includes thermal stability, chemical stability, and storage stability. Focuses on the propensity of proteins to denature during storage and use.
  • Test stability under various conditions to optimize formulation and ensure long-term efficacy and safety.
  • Use technologies such as differential scanning calorimetry (DSC) to determine thermal stability.
  • Apply circular dichroism (CD) to monitor structural changes over time.
Solubility Relates to how easily the protein or peptide dissolves in various solvents.
  • Determine solubility to guide formulation and determine the delivery methods, crucial for effective protein or peptide administration.
  • Apply saturation shake-flask method, and dynamic light scattering (DLS) methods to conduct the solubility determination.
Viscosity Describes the thickness and flow properties of protein/peptide solutions.
  • Measure viscosity to facilitate syringe ability and injectability studies, crucial for parenteral administration.
  • Utilize rotational viscometers and rheometry to determine the viscosity.
  • Chemical Property Analysis
Description Services
Charge heterogeneity Refers to variations in charge due to different molecular forms or modifications.
  • Charge profile analysis using techniques like capillary isoelectric focusing (cIEF) and ion exchange chromatography (IEX).
Isoelectric point The pH at which a protein or peptide has no net electric charge.
  • Determine isoelectric point to predict solubility and stability, crucial for purification and formulation processes.
Hydrophobic and hydrophilic Describes the water-loving (hydrophilic) and water-fearing (hydrophobic) properties of amino acids in proteins or peptides.
  • Analyze hydrophobicity/hydrophilicity to predict behavior in biological systems and inform delivery system design.
  • Use techniques like isoelectric focusing (IEF) and 2D gel electrophoresis.
Post-translational modifications Chemical modifications occur after protein synthesis, such as phosphorylation or glycosylation.
  • Identify and quantify post-translational modifications to understand their impact on protein function and immunogenicity.

Service Workflow

Our protein and peptide basic property analysis service tailored for preclinical applications initiates with an in-depth initial consultation to ascertain project specifics and collaboration frameworks. Upon agreement on cooperation terms, we formalize the partnership through a contractual agreement. Subsequently, our experts will devise the experimental methodologies and oversee the implementation of these services. Following the data collection phase, we conduct a thorough analysis of the results, culminating in the delivery of detailed, professional reports to our clients. This comprehensive approach ensures that our clients receive precise, actionable insights for their preclinical research needs.

Fig.2 The service workflow for basic property analysis of veterinary therapeutic proteins and peptides. (BioVenic Original)Fig.2 The veterinary therapeutic protein and peptide basic property analysis service workflow. (BioVenic Original)

Why Choose Us?

Equipped with advanced equipment and a team of professional experts, we deliver high-quality and precise basic property analysis for therapeutic proteins and peptides.

Our team provide a customized and one-stop solution for therapeutic protein and peptide property determination and analysis, tailored to meet the specific needs for each client.

We also offer comprehensive technical support and after-sales service to ensure our clients fully understand and can effectively utilize their data.

The basic property analysis of protein and peptide is essential for the client to ensure the purity and quality of their products. BioVenic specializes in the determination and analysis of these basic properties by utilizing innovative technologies and equipment. We offer tailored, one-stop solutions for the development and production of therapeutic proteins and peptides applying many species, including companion animals, poultry, and livestock. If you are interested in our service, please contact us now.

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