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Animal Amniotic Fluid Metabolomics
Animal Amniotic Fluid Metabolomics Services
Amniotic fluid is a transparent, watery tissue fluid that provides real-time information on fetal development and metabolism throughout pregnancy among mammals, which serves several essential functions during fetal development in the amniotic cavity. The metabolic characteristics of maternal amniotic fluid provide new ways to describe and characterize prenatal development. Analyzing its metabolism can aid in diagnosing pregnancy-related diseases and monitoring fetal development progress. BioVenic offers tailored metabolomics solutions for scientific research projects that investigate the growth, development, metabolic processes, maternal-fetal interactions, and pregnancy of animal fetuses. Through a high-throughput biochemical detection platform, we enable scientific researchers to utilize the powerful tool of amniotic fluid metabolic mapping to analyze physiological changes throughout the entire process of fetal development.
Fig.1 Amniotic Fluid Metabolic Characteristics Research in Mid-trimester Pregnancy. 1
Animal Amniotic Fluid Metabolomics Services
Amniotic fluid plays a significant role as a metabolomic substrate, reflecting fetal metabolism. The composition of lipids, phospholipids, urea, carbohydrates, and proteins in amniotic fluid changes during pregnancy and reflects the health of both the fetus and the mother. Our metabolomics analysis service, which utilizes amniotic fluid as the sample matrix, primarily relies on NMR, GC-MS, and LC-MS techniques to identify a wide range of low molecular weight compounds found in amniotic fluid. As a powerful high-throughput analysis method, this service primarily supports scientific research in the following areas:
- Animal Pregnancy Process Research
Metabolomic analysis of biomarker levels and changes in amniotic fluid can characterize each pregnancy cycle stage. BioVenic completes an in-depth assessment of the normal pregnancy process by monitoring changes in some typical metabolites, such as blood sugar, carnitine, amino acids, lactate/pyruvate (L/P) ratio, creatinine, and other metabolites. This helps to understand the mechanisms of animal fetal development and maternal health during pregnancy.
- Animal Prematurity and Underdevelopment
Untargeted metabolomics of amniotic fluid has been used in comprehensive studies to assess preterm birth. Our metabolomics service monitors high levels of common biomarkers, such as amino acids and their derivatives, as well as small molecule metabolites. This comprehensive assessment allows us to evaluate intramembranous inflammation, infection, and placental function. This assessment can be used to predict preterm birth and complications associated with prematurity, such as bronchopulmonary dysplasia. BioVenic's animal amniotic fluid metabolomics solutions also provide new high-throughput tools for researching immune status and targeted therapies during pregnancy.
- Disease-Relevant Animal Amniotic Fluid Metabolomics
BioVenic offers personalized amniotic fluid metabolomics services for research purposes. These services aim to discover novel biomarkers that can predict maternal diseases during pregnancy and assess fetal congenital diseases and overall health status. Metabolomics is a unique and reliable new tool that you can trust in the research on maternal nutrition during pregnancy.
Flow Chart of Animal Non-targeted Metabolomics Analysis Service
Amniotic Fluid Metabolomics Applications
| Monitoring of Fetal Growth and Development | Untargeted metabolomics, combined with biochemical analysis of amniotic fluid samples, can effectively monitor, and prevent major issues in mammalian pregnancy, such as fetal loss and intrauterine growth restriction. |
| Metabolic Fingerprints in Pregnancy Complications | Studies evaluating the metabolomic information of amniotic fluid in animals can reveal metabolic changes in various stages of mammalian pregnancy and offer detailed metabolic fingerprints. |
| Feed Development for Pregnant Animals | Maternal overnutrition or undernutrition during animal pregnancy significantly affects embryonic development and has important consequences for later survival. Amniotic fluid metabolomics research explores the impact of maternal nutrition on amniotic fluid composition, providing a comprehensive description and valuable perspective. This research also offers a theoretical foundation for developing feed for pregnant animals. |
Why Choose Us?
Animal amniotic fluid metabolomics solutions that support a variety of scientific uses such as optimizing individualized treatment and nutritional guidance, assessing drug-related efficacy or toxicity, identifying phenotypic changes associated with disease onset/progression, and improving early diagnosis and prognosis.
An experienced R&D team focusing on animal metabolomics sample processing and detection.
Rigorous high-throughput metabolic data analysis and delivery of bioinformatics analysis reports that are highly consistent with customer research goals.
BioVenic has launched customized amniotic fluid metabolomics services for researchers around the world to provide real-time information on fetal development and metabolism throughout pregnancy. Monitoring fetal health through the application of metabolomics could help advance the field of understanding, diagnosing, and treating disorders of pregnancy. We have advanced animal amniotic fluid metabolomic studies and their methods as reliable tools to assess many conditions and identify biomarkers. Our various biological detection platforms, such as 1 H NMR and UHPLC, have different advantages and can be combined and used according to the specific scientific research needs of customers to complete the full analysis of metabolic signals in amniotic fluid. If you are considering metabolomics as an emerging tool to evaluate various diseases and to discover biomarkers for enhanced treatment strategies, please feel free to contact us for more information.
References
- Virgiliou, Christina, et al. "Amniotic fluid and maternal serum metabolic signatures in the second trimester associated with preterm delivery." Journal of proteome research 16.2 (2017): 898-910.
- Shan, Jinjun, et al. "Metabolomics of the amniotic fluid: Is it a feasible approach to evaluate the safety of Chinese medicine during pregnancy?." Journal of Applied Toxicology 39.1 (2019): 163-171.