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Precision Goat Breeding
Goats are classic economic animals, providing meat, milk, fiber, and other products to humans around the world. Developments in animal genetics research have opened new avenues for improving goat breeds, not only by shortening the breeding time but also by expanding the range of selectable traits. The vast database provided by precision breeding enables individuals to enhance goat breeds in a more targeted manner, focusing on aspects like disease resistance, milk production, and meat quality. This accelerates the enhancement of the health and productivity of the sheep flock. BioVenic applies transgenic technology and gene editing to goats to enhance their quality. Our comprehensive goat precision breeding solution integrates genome engineering, molecular biology, genetic breeding, and big data bioinformatics. We are dedicated to addressing customer project challenges by identifying, utilizing, and integrating the advantageous traits of goats.
Fig.1 Flow Chart of Transgenic Goat Breeding1,2.
One-stop Solution Goat Genetic Modification
Based on genetic modification technology and an independently constructed animal genetic breeding database, BioVenic can alter the phenotype of goats or introduce functional genes that cannot be achieved through natural evolution. The one-stop genomic modification solution allows customers to explore key factors that can effectively improve goat productivity, reduce feeding costs, and enhance welfare and health. Goat genome editing services support the creation of cell or animal models to study metabolism-related mechanisms.
Flow Chart of One-stop Animal Gene Editing Solution
Precision Breeding in Goat
Drawing on years of project experience in the fields of animal genetics, breeding, and molecular biology, BioVenic has compiled a library of gene targets closely associated with economic traits in goats and common disease targets. Our expert technical team has conducted in-depth and thorough research on the functional genome of goats, offering robust theoretical support for the design and development of research plans. This ensures that customers' diverse needs are met through customized precision goat breeding solutions with high feasibility. Goat precision breeding services focus on developing disease-resistant varieties, improving production performance, molecular manipulation of milk components, enhancing reproductive performance, etc.
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Disease-resistant Variety Development
BioVenic offers dependable gene editing and transgenic goat breeding solutions to enhance resistance to diseases. At the same time, in the realm of researching and understanding the pathogenesis of diseases, precision breeding services have developed effective disease models. Our technology is a powerful tool for exploring projects related to goat health and welfare strategies. -
Muscle and Fiber Growth Promotion
The meat and fiber of goats are important economic products in animal husbandry. BioVenic integrates genomic targets associated with goat growth and hair fiber quality and quantity, enabling precise genomic modifications to enhance selection accuracy for economically significant traits, thus expediting agricultural production. -
Milk Components Molecular Manipulation
The precision goat breeding service launched by BioVenic involves using gene editing and transgenic technology to manipulate the composition of goat milk. This not only supports the use of transgenic technology and gene knock-in to enhance milk components but also endorses the removal of allergens in dairy products by inhibiting protein expression or gene knock-out. -
Reproductive Performance Improvement
BioVenic's precision breeding program is a potent scientific tool for enhancing the reproductive performance of goats. We utilize genetic-level manipulations, such as gene editing and transgenics, to introduce desirable traits related to fertility, such as lambing number, into goats.
| Traits | Gene | Gene ID | Functions |
|---|---|---|---|
| Muscle | MSTN | 100860887 | Prevents excessive growth of muscle tissue at all stages of organism development. |
| Fiber | FGF5 | 102171226 | Key regulator of mammalian hair length. |
| EDAR | 102179206 | Encodes the epithelial auxin A receptor and affects hair follicle development. | |
| Milk | BLG; LGB; Beta-LG | 100861187 | Encodes β-lactoglobulin. |
| DGAT1 | 100126245 | Genes critical for milk production and encodes key enzymes that control the primary pathway for TAG synthesis in adipose tissue. | |
| Reproduce | NANOS2 | 102174240 | Involved in germ cell development and maintenance of primordial germ cells (PGCs) and germline stem cells. |
| GDF9 | 100860859 | Growth differentiation factor and has a significant impact on individual litter size. | |
| Resistance | PRNP; PrP | 102169975 | Encodes a membrane glycoprotein on the outer surface of neurons, lymphocytes, and other cells and is directly involved in the development of prion-mediated diseases. |
Why Choose Us?
Team of experts in the fields of cell biology, animal breeding, and molecular biology monitors the progress of the project throughout the process.
Accurately grasp the practical key points of mammalian gene editing and transgenic technology.
Customized precision goat breeding and gene editing solutions tailored to meet customers' specific requirements.
Supported by a self-built goat genome target information database with extensive coverage.
BioVenic offers tailored services to clients worldwide in scientific disciplines like goat genome editing, cost-effective breeding, and disease mechanism research. We utilize cutting-edge gene editing and transgenic technologies to create comprehensive, scientific, and rational project plans to address the diverse scientific research requirements of our customers in the field of goat breeding. We employ biostatistical data processing to deepen our comprehension of target genes, their associated phenotypes, and functions. If you are conducting research related to goat phenotypes, please contact us to get your project started.
References
- Skrzyszowska, Maria, and Marcin Samiec. "Generating cloned goats by somatic cell nuclear transfer—Molecular determinants and application to transgenics and biomedicine."International journal of molecular sciences 22.14 (2021): 7490.
- Image retrieved from Figure 1 "Generation of transgenic cloned goats by somatic cell nuclear transfer (SCNT)". Skrzyszowska, Maria, et al., 2021, used under CC BY 4.0. The original image was modified by changing title to "Flow Chart of Transgenic Goat Breeding".