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Ruminant Digestion and Absorption Solution
At BioVenic, we provide a comprehensive solution for researchers studying ruminant digestion and absorption. Our all-in-one solution aims to enhance knowledge on the impact of diet and microbiota, shedding light on their effects on gastrointestinal tract growth and barrier function. With our solution, researchers can develop targeted management regimens to effectively influence the gut function of ruminants, leading to improved outcomes.
Ruminant Digestion and Absorption One-Stop Solution
BioVenic specializes in the development of comprehensive models for studying ruminant digestion and absorption. By understanding the unique characteristics of different ruminant species such as their digestive tracts and microbial communities, we offer in vitro and in vivo modeling and study services to explore nutrient digestion, absorption mechanisms, and identify novel biomarkers.
Ruminant Digestion and Absorption In Vitro Services
We provide a one-stop solution for In Vitro Animal Digestion Model Development of ruminants, mainly including in vitro rumen fermentation models and gastrointestinal epithelial cell culture models. We develop customized in vitro models for specific ruminants, digestive tract components, and research needs, providing targeted detection and analysis services for microorganisms, metabolites, gene expression, and more.
For more details about ruminant in vitro nutrition models, please visit the following link.
Ruminant Digestion and Absorption In Vivo Services
Our one-stop solution for in vivo study development enables researchers to investigate specific nutrient digestion and absorption in live ruminants. Through model construction, validation, optimization and application, we facilitate studies on feed testing, ruminant metabolite testing, rumen microbial analysis and more. Our ruminant digestion and absorption model building solutions cover a wide range of ruminants, including cattle, goats, sheep and more.
Fig. 1 Ruminant digestion process1,2
Ruminant Animal Digestive and Absorption Function Assays
- Endogenous Enzymatic Assays for Ruminant Animals
We conduct comprehensive digestive function testing, including assessing endogenous enzymatic solutions for ruminant animals. By examining enzyme activity and properties, we help evaluate the capability of ruminant digestive systems to efficiently utilize nutrients. Additionally, we offer natural or recombinant ruminant endogenous digestive enzymes for in vitro ruminant digestion model development
Click the following link for more information on our enzyme development services.
Table. 1 Endogenous enzyme found in the alimentary tract of cattle
| Lipases | Proteases | Carbohydrases | Others |
|
Salivary lipase Pancreatic lipase Pancreatic phospholipase |
Pepsin Rennin Trypsin Chymotrypsin Pancreatopeptidase E Carboxypeptidase A Carboxypeptidase B |
Pancreatic amylase Lactase Cellobiase Trehalase Maltase Isomaltase |
Ribonuclease Deoxyribonuclease Alkaline phosphatase |
- Ruminant Microbial Enzymatic Assays
The hydrolysis of challenging substrates by ruminal microbes necessitates a diverse range of enzymes with specificities. At BioVenic, we offer services for enzyme characterization, identification, isolation, purification, and recombinant expression of microbial enzymes derived from ruminal bacteria, fungi, and protozoa. Through our integrated platforms, we provide valuable insights into the digestive capabilities of rumen microorganisms and investigate numerous microbial enzyme resources within the rumen microbiome.
For further information, please refer to our feed enzyme additive development services.
- Ruminant Gastrointestinal Hormones Solutions
Ruminants experience variations in the composition and amount of digesta entering the abomasum, which triggers variable secretion of hydrochloric acid and adaptation of the antro-duodenal motor profile. These gastric functions can be regulated by gastrointestinal hormones. At BioVenic, we provide assays for ruminant gastrointestinal hormones like secretin, CCK, gastrin, PYY, GLP-1, and GLP-2. Our assays are tailored to specific ruminant species, and we also offer customized assay development services for ruminant gastrointestinal hormones.
- Ruminant Gastrointestinal Absorption Function Assays
The rumen serves as the primary site for absorbing volatile fatty acids (VFAs) resulting from microbial fermentation. Ruminant absorption mechanisms for protein and nucleic acid digestion products appear similar to those found in nonruminants. BioVenic offers a range of assays for indicators of rumen and intestinal absorption capacity, including immunological assays, gene expression assays, and more. These assays help researchers study the effects of genes and environmental factors on nutrient metabolite absorption in different sections of the ruminant digestive tract.
- Ruminant Gastrointestinal Permeability/ Barrier Function Assays
The permeability or barrier function of the gastrointestinal tract in ruminants can be assessed by analyzing abnormal metabolites in ruminant blood and barrier markers in gastrointestinal tissue. At BioVenic, we provide various immunoassays, protein expression level analysis, and other tailored solutions for ruminant animals. Common biomarkers such as tight junction proteins, mucins, and IgA in the rumen and intestines can be measured, facilitating species-specific and tissue-specific analysis.
Please check the following links for more information on our services.
Microbial Solutions for Ruminant Digestion and Absorption
With our state-of-the-art high-throughput sequencing platforms, we offer ruminant nutrition researchers a comprehensive microbiota analysis service. In addition to providing sequencing data, we also assist with analysis and biological interpretations, allowing for a holistic understanding of the ruminant microbiota.
The rumen microbiota consists of various microorganisms including bacteria, fungi, protozoa, and more. Microbial proteins and metabolites, such as volatile fatty acids and vitamins, provide essential nutrients for ruminants. However, some toxic microorganisms may generate metabolites that can affect ruminant health. Utilizing advanced detection technologies like chromatography, we provide metabolite analysis services for diverse microbial metabolites within the rumen.
Ruminant Animal Feed Analysis
BioVenic offers both wet chemical and NIR analysis platforms to detect nutritional composition and energy in various feed and animal samples, including forage, concentrated feed, TMR, feces, urine, and more.
Applications
- Gastrointestinal Function Research
Studying ruminant digestion and absorption offers profound insights into gastrointestinal functionality in ruminants, such as examining rumen responses to rapidly fermentable carbohydrates.
- Feed Strategy Development
Through investigations utilizing in vivo and in vitro ruminant models, animal nutritionists can assess the digestibility, bioavailability, and functional attributes of nutrients. This knowledge aids in refining ruminant feed formulations and innovating new feeds or additives.
- Mechanism Research
Employing omics and other methodologies to explore the interactions among microbiota, animal physiology, and nutrients during digestion and absorption enables researchers to identify key genes, microorganisms, and nutrients. This understanding leads to the development of novel strategies to enhance the nutritional and health profiles of ruminants.
- Biological Resource Development
The diverse array of rumen microorganisms includes potential probiotics and enzyme-producing microbes that play roles in feed biodegradation. Rumen microbiota serves as a valuable source of biological resources for advancements in animal nutrition research.
Why Choose Us?
We offer tailored solutions for ruminants, enabling the detection of feeds, metabolites, enzymes, and microorganisms with our cutting-edge detection platform.
Our team possesses extensive research acumen in ruminant nutrition, swiftly grasping your research requirements and providing corresponding solutions.
Dedicated to ruminant digestion and absorption research, we are committed to delivering innovative and distinctive research perspectives to our customers.
BioVenic's services, including in vivo and in vitro model development, feed and metabolite analysis, digestive function analysis, absorption function analysis, gastrointestinal permeability testing, and microbial testing, have broad applications spanning ruminant feed development, gastrointestinal function research, mechanism exploration, and biological resource development. If you are interested in our rumination digestion and absorption solutions, please contact us.
References
- Image retrieved from Figure 1 " Ruminant digestion process. Note: Gastrointestinal tract of ruminants and main biochemical processes occurring in it." Lozano et al., 2017, used under [CC BY 3.0]. The original title was changed to "Ruminant digestion process."
- Lozano, Marleny Garcia, et al. "Livestock methane emission: microbial ecology and mitigation strategies." Livestock Science SelimSekkin, IntechOpen (2017): 51-69.