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Monogastric Animal Digestion and Absorption Solution
The gastrointestinal tract (GIT) of animals presents a complex environment with constantly changing volumes and pH conditions. In animals, digestion and absorption are crucial processes that convert feed into absorbable nutrients, allowing them to enter the bloodstream. Unlike ruminants, such as cows, monogastric animals like pigs, poultry, horses, dogs, and cats primarily rely on enzymatic digestion for nutrient breakdown. BioVenic offers specialized solutions for research focused on monogastric animal digestion and absorption.
Monogastric Animal Digestion and Absorption One-Stop Solution
Our monogastric digestion and absorption research service encompasses a wide range of in vitro and in vivo models to suit your research needs. We assist in selecting appropriate models and provide comprehensive solutions for model design, evaluation, optimization, and application.
Monogastric Animal Digestion and Absorption In Vitro Study
In vitro studies require accurate models that simulate the complexity of the GIT to enhance the reliability of results. For monogastric animals, our In Vitro Animal Digestion Model Development service can assist in developing static and dynamic models for in vitro digestion systems. Our in vitro models, including cell models and organoids, provide excellent tools to investigate various aspects of intestinal epithelial function, such as transport, bacterial interactions, and the effects of nutrients and feed on commonly measured parameters. Some examples of in vitro animal digestion and absorption models are as follows:
| Cell Models | Organoids |
|
IPEC-J2 IPI-2I IPEC-1 CLAB PoM |
Porcine intestinal organoids Chicken embryo intestinal epithelial organoids Canine intestinal organoids Feline intestinal organoids Equine intestinal organoids |
Fig. 1 Intestinal structure, crypt location, and organoid formation1
Monogastric Animal Digestion and Absorption In Vivo Study
Each monogastric species possesses unique digestive and absorptive functions. Based on the physiological characteristics of the animal species, the type of nutrients involved, and relevant literature or prior experience, we design in vivo digestion and absorption models tailored to your research goals. Our in vivo models encompass a wide range of monogastric animal species and are applicable to animals at different stages of development, including:
- Pigs: piglets, fattening pigs, and sows
- Poultry: chickens, ducks, etc.
- Companion animals: canines and felines.
Monogastric Animal Digestive and Absorption Function Assays
- Enzymatic Assays for Monogastric Animals
Digestive enzymes play a vital role in the breakdown of nutrients within the digestive tract of monogastric animals. We provide multiple assays for digestive enzymes in monogastric animals, including measurements of enzyme activity and enzymatic characteristics. Our offerings encompass a variety of natural digestive enzymes purified from monogastric animals, as well as recombinant enzyme production services for the development of suitable digestive enzymes that align with your in vitro digestive model Click the following link for more information on our enzyme development services.
- Gastrointestinal Hormone Assays
Gastrointestinal hormones, in conjunction with the nervous system, regulate the motor, secretion, and absorption functions of the digestive organs. We offer a wide array of gastrointestinal hormone analysis service and related products specifically designed for monogastric animals. Our services also include the development of novel gastrointestinal hormone assays catering to the needs of monogastric animals.
| Gastrin | Ghrelin | Leptin | Somatostatin |
| Secretin | GIP | CCK | Motilin |
| PYY | GLP-1 | GLP-2 | OXM |
- Monogastric Animal Gastrointestinal Absorption Function Assays
The intestine serves as the main site of nutrient absorption in monogastric animals. To evaluate nutrient absorption function, we provide various solutions for the detection of proteins related to intestinal absorption. These solutions encompass immunoassays, qPCR assays, proteomics assays, and more. We also offer customization options to develop assays aligned with your specific research needs.
- Monogastric Animal Intestinal Permeability/ Barrier Function Assays
Intestinal permeability and barrier function significantly influence nutrient absorption and overall animal health in monogastric animals. We offer solutions for assessing various indicators of intestinal permeability or barrier function in monogastrics. Our solutions encompass the following common indicators of intestinal function, and we also aid in discovering new indicators.
| Mucin | IgA | LPS |
| Diamine oxidase (DAO) | D-lactate | FABP |
| Tight junction proteins | Transepithelial electrical resistance (TEER) | etc. |
Please check the following links for more information on our services.
Monogastric Animal Feed Analysis
The determination of nutrients and metabolites plays a critical role in monogastric animal digestion and absorption research. We offer feed analysis services for various nutrients, enabling the detection of crude protein, crude fiber, fat, energy, and more in feed, digesta, and fecal samples. Our detection indicators can be customized according to the specific research requirements of monogastric animals. By utilizing our feed analysis services, researchers can establish proper nutritional formulas and calculate digestibility and bioavailability.
Applications
- Feed Development
By evaluating the digestion and absorption of individual feeds, feed additives, or feed formulations within the monogastric animal digestive system, animal nutritionists can assess feed quality and effectiveness.
- Mechanistic studies
Certain functional additives can enhance digestion and absorption in monogastric animals, leading to improved growth and other desired effects. Our solutions can elucidate the underlying mechanisms behind these improvements.
- Biomarker Discovery
Through omics approaches, it becomes possible to compare metabolomic or proteomic profiles of groups of animals with varying digestive and absorptive functions. This facilitates the discovery of new markers, aiding the development of diagnostic and detection indicators specific to monogastric animals.
- Assessment of Health Status
Normal digestion and absorption are integral to the overall health of monogastric animals. Studying digestion and absorption in these animals helps in assessing their health under specific physiological and nutritional conditions.
Why Choose Us?
We specialize in monogastric animal nutrition research and provide solutions tailored to the physiological characteristics of the respective animal species.
Our team members possess backgrounds in animal-related research, enabling them to quickly grasp your research requirements and recommend suitable services.
We have established extensive collaborations with internal and external research platforms, allowing us to synthesize key information in monogastric animal nutrition research and provide customized solutions.
By leveraging our expertise in the digestion and absorption of various monogastric animals like pigs, poultry, horses, cats, and dogs, BioVenic offers comprehensive digestion and absorption solutions for monogastric animal nutrition researchers. Our solutions cover in vitro and in vivo animal studies, feed analysis, animal metabolite assays, assays for animal digestion and absorption-related enzymes, hormones, and more. We aim to provide valuable insights for your feed development, animal health research, mechanistic studies, biomarker discovery, and other endeavors. If you require assistance with monogastric animal digestion and absorption research, please don't hesitate to contact us.
Reference
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Ma, Panpan, et al. "Porcine intestinal organoids: Overview of the state of the art." Viruses 14.5 (2022): 1110.
under Open Access license CC BY 4.0, without modification.