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Mouse Anti-Canine Interleukin 1 Alpha (IL1a) Monoclonal Antibody-[Biotin]

Cat. No.VD11N936

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for canine interleukin 1 alpha. It is affinity purified by protein A. It can be applied to ELISA, WB, IHC and IF/ICC assays of canine interleukin 1 alpha.

Specifications

Application ELISA; WB; IHC; IF/ICC
Clonality Monoclonal
Classification Primary Antibody
Clone J20N24
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Interleukin 1 Alpha
Isotype IgG
Immunogen Recombinant protein of interleukin 1 alpha
Purification Protein A Purified
Conjugation Biotin
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, 50% Glycerol
Physical State Liquid

Target Information

Canine interleukin 1 alpha (IL-1α) is a key pro-inflammatory cytokine involved in regulating immune responses and initiating inflammation. It is produced by various cell types, including monocytes, macrophages, and fibroblasts, and is released upon cell damage or necrosis. IL-1α acts as an "alarmin," triggering a cascade of inflammatory responses by binding to the IL-1 receptor type 1 (IL-1R1), similar to its homolog IL-1β. This cytokine plays a crucial role in the activation of immune cells, promotion of fever, and regulation of acute-phase responses.

Target Canine Interleukin 1 Alpha
Target Synonym IL1a
Gene ID 403782
UniProt ID O46612

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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