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Mouse Anti-Porcine Doublecortin-Like Kinase 1 (DCLK1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for doublecortin-like kinase 1. It is affinity purified by protein G. It can be applied to WB, IHC, IF-P, ELISA and FC assays of doublecortin-like kinase 1.
Specifications
Target Information
Porcine doublecortin-like kinase 1 (DCLK1) is a member of the doublecortin (DCX) family of proteins, which are microtubule-associated kinases known for their roles in the development and plasticity of the nervous system. DCLK1, in particular, is involved in the regulation of microtubule dynamics, which is crucial for neuronal migration, axonal growth, and dendritic morphogenesis. As a molecular target, DCLK1 is significant due to its association with various aspects of neuronal function and its potential implications in neurodevelopmental disorders and neurodegenerative diseases. It has been studied in the context of conditions such as autism spectrum disorder, epilepsy, and certain types of cancer that exhibit aberrant neuronal characteristics.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Broner, Esther C., et al. "Doublecortin-like kinase 1 (DCLK1) is a novel NOTCH pathway signaling regulator in head and neck squamous cell carcinoma." Frontiers in Oncology 11 (2021): 677051.