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Mouse Anti-Porcine Phosphoenolpyruvate Carboxykinase Mitochondrial (PEPCK) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine phosphoenolpyruvate carboxykinase mitochondrial. It is purified by affinity chromatography. It can be applied to WB assay of porcine phosphoenolpyruvate carboxykinase mitochondrial.
Specifications
Target Information
Porcine Phosphoenolpyruvate Carboxykinase Mitochondrial (PEPCK-M) is a key mitochondrial enzyme encoded by the PCK2 gene. It catalyzes the conversion of oxaloacetate to phosphoenolpyruvate, a critical step in gluconeogenesis and the link between the TCA cycle and glycolysis. This enzyme is essential for maintaining metabolic homeostasis and is highly conserved across species, including pigs. PEPCK-M is predominantly expressed in the liver and kidneys, and its activity is regulated by hormones such as glucagon and insulin. In porcine studies, PEPCK-M has been shown to be upregulated by treatments like beta-adrenergic agonists, highlighting its role in metabolic regulation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Brown, David M., et al. "Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M) and serine biosynthetic pathway genes are co-ordinately increased during anabolic agent-induced skeletal muscle growth." Scientific reports 6.1 (2016): 28693.