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Bovine Caldesmon 1 (CALD1) ELISA Kit-Sandwich

Cat. No.EK12F174

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Caldesmon 1 (CALD1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Caldesmon 1 (CALD1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine CALD1.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Caldesmon is a calmodulin-binding protein. It tonically inhibits the ATPase activity of myosin in smooth muscle. Its conserved domain binds to several molecules, including calmodulin, actin, tropomyosin, myosin, and phospholipids. Bovine Caldesmon 1 is encoded by the CALD1 gene in cattle. Caldesmon serves as a potent inhibitor of the actin-tropomyosin activated myosin MgATPase. It can regulate actin cytoskeleton by direct actin-binding.

Target/Biomarker Bovine CALD1
Target Synonym caldesmon 1; non-muscle caldesmon; CDM; L-caldesmon; caldesmon, smooth muscle
Gene ID 281660
UniProt ID Q27976

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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References

  1. Virtanen, V. et al. Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer. Oncogenesis. 2023, 12: 42.
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