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Bovine Endonuclease 8-Like 3 (NEIL3) ELISA Kit-Sandwich

Cat. No.EK12F68

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Endonuclease 8-Like 3 (NEIL3) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Endonuclease 8-Like 3 (NEIL3) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine NEIL3.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Endonuclease 8-Like 3 (Neil3) is a DNA glycosylase involved in the base excision repair pathway. It safeguards cells from oxidative DNA damage by excising a wide range of cytotoxic and mutagenic base lesions. Bovine Endonuclease 8-Like 3 is encoded by the NEIL3 gene in cattle. Neil3 exhibits DNA glycosylase activity and AP-lyase activity specific for ssDNA and is considered the main DNA glycosylase for removal of hydantoins in ssDNA.

Target/Biomarker Bovine NEIL3
Target Synonym nei like DNA glycosylase 3; endonuclease 8-like 3; DNA glycosylase/AP lyase Neil3; endonuclease VIII-like 3; nei endonuclease VIII-like 3; nei-like protein 3
Gene ID 515343
UniProt ID Q3MHN7

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Jalland, C. M. O. et al. Neil3 induced neurogenesis protects against prion disease during the clinical phase. Scientific reports. 2016, 6: 37844.
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