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Mouse Anti-Bovine Beta-Secretase 1 (BACE) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for bovine beta-secretase 1. It is purified by affinity chromatography. It can be applied to WB assay of bovine beta-secretase 1.
Specifications
Target Information
Bovine Beta-Secretase 1 (BACE1) is a transmembrane aspartyl protease that plays a pivotal role in the amyloid pathway, particularly in the production of amyloid beta-peptides (Aβ) found in Alzheimer's disease (AD). It catalyzes the initial cleavage of the amyloid precursor protein (APP), generating Aβ peptides that aggregate to form amyloid plaques. BACE1 is highly conserved across species, including bovine, and its activity is tightly regulated. Inhibition of BACE1 has been a major focus in Alzheimer's disease research due to its critical role in Aβ generation.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.