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Mouse Anti-Porcine ADAM Metallopeptidase Domain 8 (ADAM8) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for adam metallopeptidase domain 8. It is affinity purified by protein G. It can be applied to WB, FC and ELISA assays of adam metallopeptidase domain 8.
Specifications
Target Information
Porcine ADAM metallopeptidase domain 8 (pADAM8), also known as a disintegrin and metalloproteinase 8, is a member of the ADAM (A Disintegrin And Metalloprotease) family of proteins. These proteins are multidomain enzymes that play crucial roles in various physiological processes, including cell adhesion, migration, and signaling, particularly in the context of the immune system and tissue remodeling in pigs. pADAM8 is characterized by its ability to cleave extracellular matrix proteins and cell surface proteins, which can modulate cell-cell interactions and influence cellular responses to environmental cues. It is involved in the regulation of inflammatory responses and has been implicated in the pathogenesis of various diseases, including autoimmune conditions and cancer.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Mierke, Claudia Tanja. "The versatile roles of ADAM8 in cancer cell migration, mechanics, and extracellular matrix remodeling." Frontiers in cell and developmental biology 11 (2023): 1130823.