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Rabbit Anti-Canine HMGCS2 Polyclonal Antibody
Product Overview
BioVenic rabbit anti-canine HMGCS2 polyclonal antibody is specific for canine HMGCS2. It was produced in rabbit hybridoma and protein A purified. It can be applied to ELISA assay.
Specifications
Target Information
Canine HMGCS2 is an enzyme that catalyzes the condensation of acetyl-CoA with acetoacetyl CoA to form HMG-CoA, which is the second step in the mevalonate pathway. It is primarily found in the mitochondria and is involved in ketogenesis. This enzyme plays a crucial role in energy production, specifically in the process of converting food into energy. It is also associated with the regulation of certain metabolic pathways, including lipid metabolism. Notably, its abnormal expression is associated with some pathological states, such as cancer and neurodegenerative diseases. HMGCS2 is therefore a potential target for therapeutic interventions.
Shipping and Storage
This product is shipped with dry ice. Store at -20°C to -80°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wang, Yuan-Hsi, et al. "HMGCS2 mediates ketone production and regulates the proliferation and metastasis of hepatocellular carcinoma." Cancers 11.12 (2019): 1876.