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Mouse Anti-Porcine Calsequestrin 2 Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for calsequestrin 2. It is affinity purified by protein A. It can be applied to WB, IHC, IF and ELISA assays of calsequestrin 2.
Specifications
Target Information
Porcine calsequestrin 2 (pCASQ2) is a critical intracellular calcium-binding protein predominantly found in the sarcoplasmic reticulum (SR) of muscle cells. This protein plays a vital role in the regulation of calcium ion concentration, which is essential for muscle contraction and relaxation. pCASQ2 helps to buffer and sequester calcium within the SR, ensuring the rapid and controlled release of calcium needed for muscle activation. The function of pCASQ2 is particularly significant in fast-twitch muscle fibers, which require quick and precise calcium handling for high-performance activities. Any dysfunction or mutation in pCASQ2 can lead to disorders affecting muscle function, highlighting its importance in maintaining normal muscle physiology.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Park, HaJeung, et al. "Polymerization of Calsequestrin: IMPLICATIONS FOR Ca2+ REGULATION* 210." Journal of Biological Chemistry 278.18 (2003): 16176-16182.