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Mouse Anti-Porcine Calsequestrin 2 Monoclonal Antibody

Cat. No.VD8N352

Product TypeAnimal-targeted Antibodies

Size

Product Overview

BioVenic mouse monoclonal antibody is specific for calsequestrin 2. It is affinity purified by protein A. It can be applied to WB, IHC, IF and ELISA assays of calsequestrin 2.

Specifications

Application WB; IF; IHC; ELISA
Clonality Monoclonal
Classification Primary Antibody
Clone G8N5
Host Mouse
Target Species Porcine
Species Reactivity Porcine
Specificity Calsequestrin 2
Isotype IgG2
Immunogen Recombinant protein of calsequestrin 2
Purification Protein A Purified
Concentration 1500 μg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3
Physical State Liquid

Target Information

Porcine calsequestrin 2 (pCASQ2) is a critical intracellular calcium-binding protein predominantly found in the sarcoplasmic reticulum (SR) of muscle cells. This protein plays a vital role in the regulation of calcium ion concentration, which is essential for muscle contraction and relaxation. pCASQ2 helps to buffer and sequester calcium within the SR, ensuring the rapid and controlled release of calcium needed for muscle activation. The function of pCASQ2 is particularly significant in fast-twitch muscle fibers, which require quick and precise calcium handling for high-performance activities. Any dysfunction or mutation in pCASQ2 can lead to disorders affecting muscle function, highlighting its importance in maintaining normal muscle physiology.

Target Calsequestrin 2
Target Synonym Calsequestrin 2; CASQ2
Gene ID 397436
UniProt ID O18934

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Park, HaJeung, et al. "Polymerization of Calsequestrin: IMPLICATIONS FOR Ca2+ REGULATION* 210." Journal of Biological Chemistry 278.18 (2003): 16176-16182.
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