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Mouse Anti-Canine Somatotropin/Growth Hormone (GH1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine somatotropin/growth hormone. It is affinity purified by protein A. It can be applied to WB, IHC and IF/ICC assays of canine somatotropin/growth hormone.
Specifications
Target Information
Canine somatotropin, also known as growth hormone (GH), is a peptide hormone that plays a pivotal role in various physiological processes in dogs, including promoting protein synthesis, cell growth, and bone growth. It exerts its effects through the Janus kinase 2/Stat5a pathway, activating multiple downstream signaling pathways such as the STAT, MAPK, PI3K, and PKC pathways. GH also influences the immune system by priming canine polymorphonuclear neutrophil granulocytes (PMN), enhancing functions like shape change, chemotaxis, and adhesion. Additionally, it is involved in mammary gland development and has been implicated in the proliferation of canine mammary tumor cells, highlighting its potential role as a target in cancer therapy.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.