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Mouse Anti-Canine PRMT5 Monoclonal Antibody

Product Overview

BioVenic mouse monoclonal antibody is specific for canine PRMT5. It can be applied to WB and ELISA assays of canine PRMT5.

Specifications

Application WB; ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone S18N62

Host Mouse

Target Species Canine

Species Reactivity Canine

Specificity Canine PRMT5

Isotype IgG1

Immunogen Recombinant protein of PRMT5

Concentration 2 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 15mM Sodium Azide

Buffer Phosphate Buffered Saline

Physical State Liquid

Target Information

Canine protein arginine methyltransferase 5 (PRMT5) is a type II protein arginine methyltransferase enzyme that plays a significant role in various cellular processes, including transcription, splicing, translation, metabolism, signal transduction, and DNA damage repair. It is frequently overexpressed and dysregulated in both solid and hematologic tumors, making it a key player in oncogenesis and a potential therapeutic target.

Target Canine PRMT5

Target Synonym Protein arginine N-methyltransferase 5

Gene ID 480242

UniProt ID A0A8C0PPS3

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Sloan, Shelby L., et al. "Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma." PloS one 16.5 (2021): e0250839.