Rabbit Anti-Sheep Prolactin (PRL) Polyclonal Antibody

Sheep prolactin (PRL) is a hormone synthesized and secreted by the anterior pituitary gland, playing a crucial role in various physiological processes in sheep, including reproduction, immunity, and metabolism. It is particularly important for lactation, where it promotes milk secretion, and in the regulation of mammary development and transition from proliferation to secretion (lactogenesis). PRL also influences follicle growth and ovulation, with its inhibition potentially promoting follicle recruitment by increasing PIKfyve expression during the estrus stage in ewes. The hormone's role in the immune system involves direct effects on the production of CD4+ T cells and its action is mediated by the PRL receptor (PRLR) expressed on immune cells. In the context of sheep farming, PRL's functions are essential for the health and productivity of the animals, particularly in milk yield and reproductive efficiency.