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Mouse Anti-Porcine Zinc Finger Protein 36 (ZFP36) Monoclonal Antibody

Cat. No.VD8N329

Product TypeAnimal-targeted Antibodies

Size

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Product Overview

BioVenic mouse monoclonal antibody is specific for zinc finger protein 36. It is affinity purified by protein A. It can be applied to WB and ELISA assays of zinc finger protein 36.

Specifications

Application WB; ELISA

Clonality Monoclonal

Classification Primary Antibody

Clone G7N4

Host Mouse

Target Species Porcine

Species Reactivity Porcine

Specificity Zinc Finger Protein 36

Isotype IgG2

Immunogen Recombinant protein of zinc finger protein 36

Purification Protein A Purified

Concentration 2000 μg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline with 50% Glycerol, pH 7.3

Physical State Liquid

Target Information

Porcine zinc finger protein 36 (ZFP36), also known as tristetraprolin, is a multifunctional protein that plays a significant role in the regulation of gene expression in pigs. ZFP36 is characterized by the presence of zinc finger domains, which enable it to bind to specific RNA sequences, particularly in the 3'-untranslated regions (3'-UTRs) of messenger RNAs (mRNAs). This protein is involved in the control of mRNA stability and translation, and it has been shown to promote the degradation of certain mRNAs, thereby modulating the levels of specific proteins in the cell. ZFP36's activity is crucial for the regulation of inflammation, as it targets mRNAs encoding for pro-inflammatory cytokines and other immune response mediators.

Target Zinc Finger Protein 36

Target Synonym G0S24; GOS24

Gene ID 100316849

UniProt ID D0VE66

Shipping and Storage

This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Lai, Wi S., et al. "Promoter Analysis of Zfp-36 the Mitogen-inducible Gene Encoding the Zinc Finger Protein Tristetraprolin (∗)." Journal of Biological Chemistry 270.42 (1995): 25266-25272.