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Mouse Anti-Canine Cytotoxic T-Lymphocyte Protein 4 (CTLA4) Monoclonal Antibody

Cat. No.VD11N955

Product TypeAnimal-targeted Antibodies

Size 100 µg

Product Overview

BioVenic mouse monoclonal antibody is specific for canine cytotoxic T-lymphocyte protein 4. It is affinity purified by protein A/G. It can be applied to ELISA, FCM and SPR assays of canine cytotoxic T-lymphocyte protein 4.

Specifications

Application ELISA; FCM; SPR
Clonality Monoclonal
Classification Primary Antibody
Clone J20N43
Host Mouse
Target Species Canine
Species Reactivity Canine
Specificity Canine Cytotoxic T-Lymphocyte Protein 4
Isotype IgG2
Immunogen Recombinant protein of cytotoxic T-lymphocyte protein 4
Purification Protein A/G Purified
Purity > 95% (SDS-PAGE)
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.09% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4
Physical State Liquid

Target Information

Canine cytotoxic T-lymphocyte protein 4 (CTLA-4), also known as CD152, is a critical immune checkpoint molecule expressed on the surface of T cells. It is a member of the immunoglobulin superfamily and plays a key role in regulating T cell activation by transmitting inhibitory signals. CTLA-4 competes with CD28 for binding to its ligands, CD80 (B7-1) and CD86 (B7-2), thereby blocking the positive costimulatory signals required for T cell activation.

Target Canine Cytotoxic T-Lymphocyte Protein 4
Target Synonym CTLA4
Gene ID 403696
UniProt ID Q9XSI1

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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