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Mouse Anti-Porcine Ataxin 3 (ATXN3) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for ataxin 3. It is affinity purified by protein A. It can be applied to WB, IHC and ELISA assays of ataxin 3.
Specifications
Target Information
Porcine ataxin 3 (pATXN3) is a protein found within cells that plays a crucial role in various cellular processes, including protein quality control, transcriptional regulation, and cellular responses to stress. It is a deubiquitinating enzyme that can remove ubiquitin molecules from target proteins, thereby regulating protein stability and function. In pigs, pATXN3 contributes to the maintenance of neuronal health and function, as it is highly expressed in the brain and particularly in regions associated with motor control. It is involved in the clearance of misfolded proteins, which is essential for preventing the accumulation of toxic protein aggregates that can lead to neurodegenerative diseases.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Weishäupl, Daniel, et al. "Physiological and pathophysiological characteristics of ataxin-3 isoforms." Journal of Biological Chemistry 294.2 (2019): 644-661.