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Mouse Anti-Porcine Optic Atrophy 1 (OPA1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for optic atrophy 1. It is affinity purified by protein A. It can be applied to WB, IHC and ELISA assays of optic atrophy 1.
Specifications
Target Information
Porcine optic atrophy 1 (OPA1) is a protein that plays a critical role in the maintenance of mitochondrial function in pig cells. It is particularly important for the organization of the mitochondrial inner membrane, where it contributes to the formation of the cristae, the invaginations that compartmentalize the inner membrane and increase its surface area for efficient energy production. OPA1 is involved in the regulation of mitochondrial dynamics, which includes processes such as fusion and fission of the organelles. These processes are essential for the proper distribution of mitochondria within cells and for the maintenance of their overall health and function. Disruptions in OPA1 function are associated with various diseases, including optic atrophy, a condition characterized by the degeneration of the optic nerve.
Shipping and Storage
This product is shipped with ice gel packs. Store at -20°C (up to 12 months) on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Lee, Hakjoo, et al. "The short variant of optic atrophy 1 (OPA1) improves cell survival under oxidative stress." Journal of Biological Chemistry 295.19 (2020): 6543-6560.