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Mouse Anti-Porcine HtrA Serine Peptidase 1 (HTRA1) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for htrA serine peptidase 1. It is affinity purified by protein A. It can be applied to WB and Indirect ELISA assays of htrA serine peptidase 1.
Specifications
Target Information
Porcine htrA serine peptidase 1 (HTRA1) is a multifunctional serine protease that has been implicated in a variety of biological processes, including the regulation of extracellular matrix proteins and the modulation of signaling pathways such as the canonical Wnt pathway. This enzyme is secreted and has the ability to cleave its substrates in the extracellular space, affecting cellular processes like angiogenesis and inflammation. In pigs, HTRA1 may serve as a model for studying the role of this protease in AMD and other diseases. Understanding its function in the porcine model could provide insights into human disease mechanisms and potential therapeutic strategies.
Shipping and Storage
This product is shipped with ice gel packs. Store at -80°C on receipt.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Owen, Leah A., et al. "The serine protease HTRA-1 is a biomarker for ROP and mediates retinal neovascularization." Frontiers in Molecular Neuroscience 13 (2020): 605918.