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Mouse Anti-Canine Nestin Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for canine nestin. It can be applied to WB, ICC/IF and IHC assays of canine nestin.
Specifications
Target Information
Canine nestin is a class VI intermediate filament protein that is expressed in various types of cells, including neural stem/progenitor cells, and is associated with cell proliferation, migration, and resistance to apoptosis, particularly in the context of cancer. It is also found in muscle precursors and cells of the developing heart, testis, and kidney. In adult animals, nestin expression is mainly restricted to specific regions of the brain, such as the subependymal zone and dentate gyrus, as well as the neuromuscular junction and renal podocytes. Nestin's involvement in the regulation of Cdk5 activity and its phosphorylation during myogenic differentiation also highlight its importance in cellular organization and signaling pathways.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.