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Mouse Anti-Porcine IgM μ Chain Specific Monoclonal Antibody-[FITC]
Product Overview
BioVenic mouse monoclonal antibody is specific for porcine IgM μ chain. It can be applied to FCM, IF, IHC and ELISA assays of porcine IgM μ chain.
Specifications
Target Information
Porcine IgM μ chain is a crucial component of the immune system in pigs, playing a significant role in the primary immune response. It is characterized by its high molecular weight and a pentameric structure, consisting of five subunits and a single J-chain. Each subunit comprises a pair of heavy (μ) and light chains, with the heavy chain containing one variable and four constant regions. IgM is often referred to as a macroglobulin due to its large size and is the first antibody to be produced in response to an initial exposure to an antigen. It is particularly effective at activating the complement system, a critical part of the immune response that helps to clear pathogens. The μ chain of porcine IgM is also significant in the context of vaccine development and understanding disease resistance in pigs.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid exposure to light. Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Rungelrath, Viktoria, et al. "IgM cleavage by Streptococcus suis reduces IgM bound to the bacterial surface and is a novel complement evasion mechanism." Virulence 9.1 (2018): 1314-1337.